lipopolysaccharide receptor complex

Known as: LPS receptor complex, LPS receptor complex location, lipopolysaccharide receptor complex location 
A multiprotein complex that consists of at least three proteins, CD14, TLR4, and MD-2, each of which is glycosylated and which functions as a… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1999-2017
0519992017

Papers overview

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2009
2009
Bacterial LPS triggers monocytes and macrophages to produce several inflammatory cytokines and mediators. However, once exposed… (More)
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Highly Cited
2006
Highly Cited
2006
Immune responses are initiated when molecules of microbial origin are sensed by the Toll-like receptors (TLRs). We now report the… (More)
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Highly Cited
2002
Highly Cited
2002
Human toll-like receptor 4 (hTLR4) and CD14 are known to be components of the lipopolysaccharide receptor complex. Our study… (More)
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Highly Cited
2002
Highly Cited
2002
Prior exposure to LPS induces a transient state of cell refractoriness to subsequent LPS restimulation, known as endotoxin… (More)
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Highly Cited
2001
Highly Cited
2001
The structural features of some proteins of the innate immune system involved in mediating responses to microbial pathogens are… (More)
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Highly Cited
2001
Highly Cited
2001
Macrophages are pivotal effector cells of the innate immune system, which is vital for recognizing and eliminating invasive… (More)
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Highly Cited
2000
Highly Cited
2000
Lipopolysaccharide (LPS) is the main inducer of shock and death in Gram-negative sepsis. Recent evidence suggests that LPS… (More)
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Highly Cited
2000
Highly Cited
2000
The exact roles and abilities of the individual components of the lipopolysaccharide (LPS) receptor complex of proteins remain… (More)
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Highly Cited
1999
Highly Cited
1999
Bacterial lipopolysaccharide (LPS)-mediated immune responses, including activation of monocytes, macrophages, and endothelial… (More)
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Highly Cited
1999
Highly Cited
1999
Human Toll-like receptor 2 (TLR2) is a signaling receptor that responds to LPS and activates NF-kappaB. Here, we investigate… (More)
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