• Publications
  • Influence
Overexpression of mouse follistatin causes reproductive defects in transgenic mice.
Follistatin is an activin-binding protein that can act as an activin antagonist in vitro. Follistatin also binds heparin sulfate proteoglycans and may function as a reservoir for activins in vivo. InExpand
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Polymorphism of CD14 gene but not the mutation of TLR4 gene is associated with colorectal cancer in Chinese patients
Objectives:  Toll‐like receptor 4 and CD14 are components of the lipopolysaccharide receptor complex. Our study aimed to investigate an association between TLR4 Asp299Gly and CD14‐260 polymorphismsExpand
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Adam10 mediates the choice between principal cells and intercalated cells in the kidney.
A disintegrin and metalloproteinase domain 10 (Adam10), a member of the ADAM family of cell membrane-anchored proteins, has been linked to the regulation of the Notch, EGF, E-cadherin, and otherExpand
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  • Open Access
Cre/lox recombination in the lower urinary tract
Tbx18 is a T‐Box transcription factor that has specific expression and indispensible function in the lower urinary tract. Here, we report the generation and characterization of a bacterial artificialExpand
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Association of diminished expression of RASSF1A with promoter methylation in primary gastric cancer from patients of central China
BackgroundAlthough methylation-mediated inactivation of expression of RASSF1A, a candidate tumor suppressor gene, has been observed in several human cancers, the data concerning alteration of RASSF1AExpand
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  • Open Access
The microenvironmental determinants for kidney epithelial cyst morphogenesis.
Although epithelial morphogenesis is tightly controlled by intrinsic genetic programs, the microenvironment in which epithelial cells proliferate and differentiate also contributes to theExpand
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Sinomenine attenuates 2, 4, 6-trinitrobenzene sulfonic acid-induced colitis in mice.
Sinomenine is a pure alkaloid extracted from the Chinese medical plant Sinomenium acutum. It was demonstrated that sinomenine had anti-inflammatory and immunosuppressive effects in the previousExpand
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Epigenetic regulation of death-associated protein kinase expression in primary gastric cancers from Chinese patients
Death-associated protein kinase (DAPK) is a novel serine/threonine kinase involved in apoptosis and tumor suppression. Promoter methylation is an important mechanism by which tumor suppressor geneExpand
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Tetraspanins regulate the protrusive activities of cell membrane.
  • R. Bari, Q. Guo, +5 authors X. Zhang
  • Biology, Medicine
  • Biochemical and biophysical research…
  • 2 December 2011
Tetraspanins have gained increased attention due to their functional versatility. But the universal cellular mechanism that governs such versatility remains unknown. Herein we present the evidenceExpand
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Midline signaling regulates kidney positioning but not nephrogenesis through Shh.
The role of axial structures, especially the notochord, in metanephric kidney development has not been directly examined. Here, we showed that disruption of the notochord and floor plate byExpand
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