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linogliride

Known as: N-(1-Methyl-2-pyrrolidinylidene)-N'-phenyl-4-morpholinecarboxamidine 
A guanidine-based insulin secratogogue and structural analogue of pirogliride with hypoglycemic activity. Linogliride blocks ATP-sensitive potassium… 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Pyrrolidines
linogliride fumarate

Papers overview

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1987
1987
Influence of the oral hypoglycemic agent linogliride (McN-3935) on insulin secretion from isolated rat islets of Langerhans.
The influence of a new orally effective hypoglycemic compound, linogliride (McN-3935), on insulin release from isolated perifused… 
1986
1986
Metabolism of linogliride (Lg) in the rat, dog and man
Lg, N-(1-methyl-2-pyrrolidinylidene)-N'-phenyl-4-morpho-linecarboximidamide, is a new hypoglycemic drug. Following oral… 
1986
1986
Process for producing guanidines such as linogliride and process for intermediates
New synthesis intermediates generated and guanidines such as anti-diabetic compound linogliride, including hydrogen peroxide… 
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