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ligase activity
Known as:
synthetase activity
Catalysis of the joining of two substances, or two groups within a single molecule, with the concomitant hydrolysis of the diphosphate bond in ATP or…
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National Institutes of Health
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Related topics
Related topics
4 relations
Ligase
negative regulation of ligase activity
positive regulation of ligase activity
regulation of ligase activity
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
Diet- and colonization-dependent intestinal dysfunction predisposes to necrotizing enterocolitis in preterm pigs.
P. Sangild
,
R. Siggers
,
+12 authors
D. Burrin
Gastroenterology
2006
Corpus ID: 23255079
BACKGROUND & AIMS Preterm birth and formula feeding are key risk factors associated with necrotizing enterocolitis (NEC) in…
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Review
2002
Review
2002
The BRCA1/BARD1 heterodimer, a tumor suppressor complex with ubiquitin E3 ligase activity.
R. Baer
,
T. Ludwig
Current Opinion in Genetics and Development
2002
Corpus ID: 24096778
Highly Cited
1990
Highly Cited
1990
Elucidation of the deficiency in two yeast coenzyme Q mutants. Characterization of the structural gene encoding hexaprenyl pyrophosphate synthetase.
M N Ashby
,
P A Edwards
Journal of Biological Chemistry
1990
Corpus ID: 25254158
Highly Cited
1985
Highly Cited
1985
Purification and characterization of rat brain prostaglandin D synthetase.
Y. Urade
,
N. Fujimoto
,
O. Hayaishi
Journal of Biological Chemistry
1985
Corpus ID: 22040925
Highly Cited
1984
Highly Cited
1984
AppppA and related adenylylated nucleotides are synthesized as a consequence of oxidation stress
B. Bochner
,
Philip C. Lee
,
Scott W. Wilson
,
C. Cutler
,
B. Ames
Cell
1984
Corpus ID: 27477595
Highly Cited
1977
Highly Cited
1977
Coronary tone modulation: formation and actions of prostaglandins, endoperoxides, and thromboxanes.
P. Needleman
,
P. Kulkarni
,
A. Raz
Science
1977
Corpus ID: 24860102
Exogenous prostaglandin (PGE2) contracts bovine and human coronary arteries but its precursor, arachidonic acid, relaxes them…
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Highly Cited
1976
Highly Cited
1976
Altered platelet function in diabetes mellitus.
J. Colwell
,
P. Halushka
,
K. Sarji
,
J. Levine
,
J. Sagel
,
R. Nair
Diabetes
1976
Corpus ID: 39063921
An increased sensitivity of platelets to aggregation from ADP and epinephrine is described in diabetics with or without vascular…
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Highly Cited
1974
Highly Cited
1974
Production and utilization of acetate in mammals.
Spencer E Knowles
,
Ivan G. Jarrett
,
Owen H. Filsell
,
F. Ballard
Biochemical Journal
1974
Corpus ID: 2783705
1. In an attempt to define the importance of acetate as a metabolic precursor, the activities of acetyl-CoA synthetase (EC 6.2.1…
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Highly Cited
1973
Highly Cited
1973
Muscle Carnitine Palmityltransferase Deficiency and Myoglobinuria
S. Dimauro
,
P. DiMauro
Science
1973
Corpus ID: 31149586
Muscle carnitine palmityltransferase activity, measured by three different methods, was very low (0 to 20 percent of controls) in…
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Highly Cited
1967
Highly Cited
1967
The relative significance of acetate and glucose as precursors for lipid synthesis in liver and adipose tissue from ruminants.
R. Hanson
,
F. Ballard
Biochemical Journal
1967
Corpus ID: 31049860
1. The incorporation of labelled glucose into lipid by liver slices from sheep and cows is considerably less than that by liver…
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