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leridistim

Known as: 14-125 interleukin-3(14-alanine, 50-aspartic acid), granulocyte colony stimulating factor(17-serine) fusion protein, MPO, Myelopoietin 
A recombinant chimeric dual G-CSF and IL-3 receptor agonist. Leridistim binds with high affinity to both the interleukin-3 (IL-3) and granulocyte… 
National Institutes of Health

Related topics

Related topics

4 relations

Broader (3)

Granulocyte Colony-Stimulating FactorInterleukin-3Recombinant Fusion Proteins
myelopoietin

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
model of radiation-induced myelosuppression stimulates multilineage hematopoietic recovery in a nonhuman primate Myelopoietin, an engineered chimeric IL-3 and G-CSF receptor agonist,
2008
2008
Novel biomarkers--the long march from bench to bedside.
In recent years, a deeper understanding of the pathobiology of atherothrombosis as the underlying mechanism of acute coronary… 
2008
2008
[Effect of growth factor on the phenotype of subpopulations and on the kinetics of CD34+ cells in the peripheral blood and in grafts of peripheral stem cells in patients with non-Hodgkin's lymphoma…
BACKGROUND Peripheral blood stem cells are the preferred source for transplantation of hematopoiesis in patients with non-Hodgkin… 
2004
2004
Preparative and analytical chromatography of pegylated myelopoietin using monolithic media.
2002
2002
Cytokine-based treatment of radiation injury: potential benefits after low-level radiation exposure.
The use of growth factors (GFs) in the treatment of radiation injury has focused on enhancing recovery from acute radiation… 
2002
2002
The enhanced in vitro hematopoietic activity of leridistim, a chimeric dual G-CSF and IL-3 receptor agonist
The in vitro activity of leridistim was characterized for cell proliferation, generation of colony-forming units (CFU) and… 
2001
2001
Phage display mutagenesis of the chimeric dual cytokine receptor agonist myelopoietin
Myelopoietins comprise a class of chimeric cytokine receptor agonists consisting of an hIL-3 (human interleukin-3) receptor… 
2001
2001
Bivalent binding and signaling characteristics of Leridistim, a novel chimeric dual agonist of interleukin-3 and granulocyte colony-stimulating factor receptors.
Review
2000
Review
2000
Synthetic cytokines containing interleukin-3 exert potent megakaryopoietic activity.
The shared properties of haematopoietic cytokines and their receptors have enabled the genetically engineered construction of… 
1999
1999
Circular permutation of the granulocyte colony-stimulating factor receptor agonist domain of myelopoietin.
Myelopoietins (MPOs) are a family of engineered dual interleukin-3 (IL-3) and granulocyte colony-stimulating factor (G-CSF… 
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