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leoligin

National Institutes of Health

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Lignans

Papers overview

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2020
2020
Characterization of a Structural Leoligin Analog as Farnesoid X Receptor Agonist and Modulator of Cholesterol Transport
Abstract The ligand-activated farnesoid X receptor is an emerging therapeutic target for the development of drugs against… 
2020
2020
Design and Synthesis of a Compound Library Exploiting 5-Methoxyleoligin as Potential Cholesterol Efflux Promoter
5-Methoxyleoligin and leoligin are natural occurring lignans derived from Edelweiss (Leontopodium nivale ssp. alpinum… 
2016
2016
Leoligin, the Major Lignan from Edelweiss (Leontopodium nivale subsp. alpinum), Promotes Cholesterol Efflux from THP-1 Macrophages
Leoligin is a natural lignan found in Edelweiss (Leontopodium nivale ssp. alpinum). The aim of this study was to examine its… 
2016
2016
Leoligin, the major lignan from Edelweiss, inhibits 3-hydroxy-3-methyl-glutaryl-CoA reductase and reduces cholesterol levels in ApoE-/- mice.
2016
2016
Online Supplementary Information to Scharinger et al. Leoligin, the Major Lignan from Edelweiss, Inhibits 3-hydroxy-3-methyl-glutaryl-CoA Reductase and Reduces Cholesterol Levels in ApoE -/- mice…
Leoligin, the Major Lignan from Edelweiss, Inhibits 3-hydroxy-3-methyl-glutaryl-CoA Reductase and Reduces Cholesterol Levels in… 
2015
2015
Screening of leoligin derivatives as NF-κB inhibitors
Nuclear factor kappa B ist eine Familie von pro-inflammatorischen Transkriptionsfaktoren, die durch verschiedene Zytokine wie… 
2014
2014
Lignan formation in hairy root cultures of Edelweiss (Leontopodium nivale ssp. alpinum (Cass.) Greuter)
2014
2014
Investigation of the effect of leoligin derivatives on vascular smooth muscle cell proliferation
Atherosklerose ist die Ursache fur das Entstehen von schwerwiegenden Ereignissen wie Schlaganfall, Herzinfarkt, Angina pectoris… 
2014
2014
Synthetic lignans targeting cardiovascular diseases
  • 2014
  • Corpus ID: 28526755
INVENTORS Marko MIHOVILOVIC Thomas LINDER Atanas ATANASOV Verena DIRSCH Hermann STUPPNER Stefan SCHWEIGER David BERNHARD Intimal… 
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