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lavendamycin

Known as: 9H-Pyrido(3,4-b)indole-3-carboxylic acid, 1-(7-amino-5,8-dihydro-5,8-dioxo-2-quinolinyl)-4-methyl- 
National Institutes of Health

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Broader (1)

Streptonigrin
analogs & derivatives

Papers overview

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2014
2014
Significance of agitation-induced shear stress on mycelium morphology and lavendamycin production by engineered Streptomyces flocculus
Lavendamycin methyl ester (LME) is a derivative of a highly functionalized aminoquinone alkaloid lavendamycin and could be used… 
2013
2013
MECHANISMS AND CYTOTOXIC EFFECTS OF NQO1-DIRECTED LAVENDAMYCIN DERIVATIVES AND MITOCHONDRIA-TARGETED ANTHRACENYL ISOXAZOLE AMIDES AS NOVEL ANTITUMOR AGENTS
A series of 7-aminoand 7-acetamidoquinoline-5,8-diones with aryl substituents at the 2position were synthesized, characterized… 
2009
2009
Total synthesis of Lavendamycin derivatives : an honors thesis (HONRS 499)
Derivatives of Lavendamycin, an antitumor antibiotic natural product, were synthesized via short and efficient methods. Pictet… 
2007
2007
NAD(P)H:quinone oxidoreductase (NQO1)-directed lavendamycin antitumor agents: Structure-based design, molecular modeling and structure-activity studies
iii Acknowledgements iv Table of 
2003
2003
Siloxane-based cross-coupling of bromopyridine derivatives: studies for the synthesis of streptonigrin and lavendamycin.
Highly functionalized 4-bromopyridines were prepared and found to undergo fluoride-promoted, Pd-catalyzed cross-coupling with… 
2003
2003
Combined effects of lavendamycin analogs and AZT on HIV-reverse transcriptase : an honors thesis (HONRS 499)
2003
2003
--Total Synthesis of 7N-Succinyldemethyllavendamycin Esters
7-N-Succinyldemethyllavendamycin esters-analogs of the naturally occurring, anti-tumor, anti-microbial agent lavendamycin-were… 
2001
2001
Biologic effects of lavendamycin analogs on cultured cells and HIV-RT
1999
1999
Anti-retroviral activity of lavendamycin analogs in combination with azt-tp
1986
1986
In vitro oxidation of the 8-hydroxyquinoline moiety with metabolic activation system to a mutagenic quinoloquinone compound of lavendamycin analogs.
Intermediary products in the synthesis of lavendamycin were tested for mutagenic activities in Salmonella typhimurium TA 98 and… 
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