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larotaxel

A semi-synthetic derivative of the taxane 10-deacetylbaccatin III with potential antineoplastic activities. Larotaxel binds to tubulin, promoting… Expand
National Institutes of Health

Papers overview

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2017
2017
1. The aim of this study was to compare the pharmacokinetics (PKs) and tissue distribution of larotaxel (LTX) solution with a… Expand
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2015
2015
Combination chemotherapy with gemcitabine and cisplatin in patients with metastatic urothelial cancer of the bladder frequently… Expand
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2014
2014
The purpose of this study was to develop a parenteral larotaxel lipid microsphere (LTX-LM) and evaluate its stability. The… Expand
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2013
2013
PurposeLarotaxel is a new taxane compound with poor solubility. The aim of this study is to develop a new formulation to locate… Expand
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Review
2009
Review
2009
Significant advances in cancer treatment have been achieved with novel targeted and state-of-the-art treatments. While the… Expand
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2009
2009
Larotaxel (XRP9881, RPR109881), a novel semi-synthetic taxoid that shares a mode of action with the taxanes docetaxel and… Expand
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Review
2009
Review
2009
Opinion statementAdvanced bladder/urothelial cancer remains an incurable terminal disease, and accounts for 3% of the cancer… Expand
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Review
2009
Review
2009
Regardless of stage of disease, cytotoxic chemotherapy remains an important part of the treatment paradigm for breast cancer… Expand
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2009
2009
PurposeThis primary objective of this phase I dose-escalation study was to define the maximum tolerated dose (MTD) and dose… Expand
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2008
2008
INTRODUCTION This randomized phase II study investigated the efficacy and safety of a new taxane, larotaxel (XRP9881), in… Expand
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