larotaxel

A semi-synthetic derivative of the taxane 10-deacetylbaccatin III with potential antineoplastic activities. Larotaxel binds to tubulin, promoting… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

2008-2018
02420082018

Papers overview

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2015
2015
Combination chemotherapy with gemcitabine and cisplatin in patients with metastatic urothelial cancer of the bladder frequently… (More)
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2014
2014
The purpose of this study was to develop a parenteral larotaxel lipid microsphere (LTX-LM) and evaluate its stability. The… (More)
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2013
2013
Larotaxel is a new taxane compound with poor solubility. The aim of this study is to develop a new formulation to locate the… (More)
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2012
2012
A simple and efficient method based on cloud-point extraction combined with high-performance liquid chromatography was developed… (More)
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2012
2012
A UPLC-ESI-MS/MS method has been developed and validated for the determination of larotaxel in beagle dog plasma. After addition… (More)
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2011
2011
The isolation and characterization of the process related impurities and degradation products of larotaxel drug substance were… (More)
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2009
2009
Larotaxel (XRP9881, RPR109881), a novel semi-synthetic taxoid that shares a mode of action with the taxanes docetaxel and… (More)
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Review
2009
Review
2009
Significant advances in cancer treatment have been achieved with novel targeted and state-of-the-art treatments. While the… (More)
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2009
2009
This primary objective of this phase I dose-escalation study was to define the maximum tolerated dose (MTD) and dose limiting… (More)
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2008
2008
INTRODUCTION This randomized phase II study investigated the efficacy and safety of a new taxane, larotaxel (XRP9881), in… (More)
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