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lactate oxidation

The chemical reactions and pathways resulting in the conversion of lactate to other compounds, such as pyruvate, with concomitant loss of electrons… Expand
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
Cerebral energy metabolism is a highly compartmentalized and complex process in which transcellular trafficking of metabolites… Expand
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Review
2009
Review
2009
  • G. Brooks
  • The Journal of physiology
  • 2009
  • Corpus ID: 206377063
Once thought to be the consequence of oxygen lack in contracting skeletal muscle, the glycolytic product lactate is formed and… Expand
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Highly Cited
2008
Highly Cited
2008
To evaluate the presence of components of a putative Intracellular Lactate Shuttle (ILS) in neurons, we attempted to determine if… Expand
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Highly Cited
2007
Highly Cited
2007
We hypothesized that in addition to serving as a fuel source and gluconeogenic precursor, lactate anion (La−) is a signaling… Expand
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Highly Cited
2003
Highly Cited
2003
Neuronal cultures in vitro readily oxidized both D-[14C]glucose and l-[14C]lactate to 14CO2, whereas astroglial cultures oxidized… Expand
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Review
2002
Review
2002
  • G. Brooks
  • Biochemical Society transactions
  • 2002
  • Corpus ID: 11287136
Once thought to be the consequence of oxygen lack in contracting skeletal muscle, the glycolytic product lactate is formed and… Expand
Is this relevant?
Highly Cited
1999
Highly Cited
1999
To evaluate the potential role of mitochondrial lactate dehydrogenase (LDH) in tissue lactate clearance and oxidation in vivo… Expand
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Highly Cited
1996
Highly Cited
1996
Metformin is a biguanide that has been shown to effectively lower plasma glucose levels in subjects with noninsulin-dependent… Expand
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Highly Cited
1995
Highly Cited
1995
BACKGROUND The metabolic effects and mechanism of action of metformin are still poorly understood, despite the fact that it has… Expand
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Highly Cited
1994
Highly Cited
1994
The contribution of glycolysis and oxidative metabolism to ATP production was determined in isolated working hypertrophied hearts… Expand
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