lactate oxidation

The chemical reactions and pathways resulting in the conversion of lactate to other compounds, such as pyruvate, with concomitant loss of electrons… (More)
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
Cerebral energy metabolism is a highly compartmentalized and complex process in which transcellular trafficking of metabolites… (More)
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Review
2009
Review
2009
Once thought to be the consequence of oxygen lack in contracting skeletal muscle, the glycolytic product lactate is formed and… (More)
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Highly Cited
2007
Highly Cited
2007
We hypothesized that in addition to serving as a fuel source and gluconeogenic precursor, lactate anion (La-) is a signaling… (More)
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Highly Cited
2003
Highly Cited
2003
Neuronal cultures in vitro readily oxidized both D-[(14)C]glucose and l-[(14)C]lactate to (14)CO(2), whereas astroglial cultures… (More)
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Highly Cited
2003
Highly Cited
2003
To study the role of muscle mass and muscle activity on lactate and energy kinetics during exercise, whole body and limb lactate… (More)
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Review
2001
Review
2001
Once thought to be the consequence of oxygen lack in contracting skeletal muscle, the glycolytic product lactate is formed and… (More)
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Highly Cited
1999
Highly Cited
1999
To evaluate the potential role of mitochondrial lactate dehydrogenase (LDH) in tissue lactate clearance and oxidation in vivo… (More)
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Highly Cited
1999
Highly Cited
1999
Previous investigations revealed low activities of lactate dehydrogenase (LDH) and plasma membrane monocarboxylate transporters… (More)
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Highly Cited
1996
Highly Cited
1996
Metformin is a biguanide that has been shown to effectively lower plasma glucose levels in subjects with noninsulin-dependent… (More)
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Highly Cited
1995
Highly Cited
1995
BACKGROUND The metabolic effects and mechanism of action of metformin are still poorly understood, despite the fact that it has… (More)
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