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lacrimal gland development

The process whose specific outcome is the progression of the lacrimal gland over time, from its formation to the mature structure. The lacrimal gland… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Defining epithelial cell dynamics and lineage relationships in the developing lacrimal gland
The tear-producing lacrimal gland is a tubular organ that protects and lubricates the ocular surface. The lacrimal gland… Expand
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2017
2017
Alx4 relays sequential FGF signaling to induce lacrimal gland morphogenesis
The sequential use of signaling pathways is essential for the guidance of pluripotent progenitors into diverse cell fates. Here… Expand
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Highly Cited
2014
Highly Cited
2014
FGF signaling activates a Sox9-Sox10 pathway for the formation and branching morphogenesis of mouse ocular glands
Murine lacrimal, harderian and meibomian glands develop from the prospective conjunctival and eyelid epithelia and produce… Expand
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Highly Cited
2012
Highly Cited
2012
Glycosaminoglycan-dependent restriction of FGF diffusion is necessary for lacrimal gland development
Glycosaminoglycans (GAGs) play a central role in embryonic development by regulating the movement and signaling of morphogens. We… Expand
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Highly Cited
2011
Highly Cited
2011
Lacrimal Gland Development and Fgf10-Fgfr2b Signaling Are Controlled by 2-O- and 6-O-sulfated Heparan Sulfate*
Heparan sulfate, an extensively sulfated glycosaminoglycan abundant on cell surface proteoglycans, regulates intercellular… Expand
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2010
2010
Sprouty2-modulated Kras signaling rescues Shp2 deficiency during lens and lacrimal gland development
Shp2/Ptpn11 tyrosine phosphatase is a general regulator of the RTK pathways. By genetic ablation, we demonstrate that Shp2 is… Expand
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2009
2009
Purification and characterization of mouse lacrimal gland epithelial cells and reconstruction of an acinarlike structure in three-dimensional culture.
PURPOSE To clarify which factors are involved in postnatal lacrimal gland development, the expressions of several growth factors… Expand
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Highly Cited
2008
Highly Cited
2008
Bud specific N-sulfation of heparan sulfate regulates Shp2-dependent FGF signaling during lacrimal gland induction
Preferential outgrowth of the bud cells forms the basis of branching morphogenesis. Here, we show that lacrimal gland development… Expand
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2006
2006
The role of the forkhead transcription factor, Foxc1, in the development of the mouse lacrimal gland
The lacrimal gland produces secretions that lubricate and protect the cornea of the eye. Foxc1 encodes a forkhead/winged helix… Expand
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Highly Cited
2000
Highly Cited
2000
FGF10 is an inducer and Pax6 a competence factor for lacrimal gland development.
We investigated the mechanism of tissue induction and specification using the lacrimal gland as a model system. This structure… Expand
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