lacrimal gland development

The process whose specific outcome is the progression of the lacrimal gland over time, from its formation to the mature structure. The lacrimal gland… (More)
National Institutes of Health

Papers overview

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Review
2016
Review
2016
Challenges and Strategies for Regenerating the Lacrimal Gland.
The lacrimal gland produces the aqueous component of tears, including electrolytes, peptides, and glycoproteins necessary to… (More)
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2014
2014
FGF signaling activates a Sox9-Sox10 pathway for the formation and branching morphogenesis of mouse ocular glands.
Murine lacrimal, harderian and meibomian glands develop from the prospective conjunctival and eyelid epithelia and produce… (More)
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2012
2012
Glycosaminoglycan-dependent restriction of FGF diffusion is necessary for lacrimal gland development.
Glycosaminoglycans (GAGs) play a central role in embryonic development by regulating the movement and signaling of morphogens. We… (More)
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2011
2011
Lacrimal gland development and Fgf10-Fgfr2b signaling are controlled by 2-O- and 6-O-sulfated heparan sulfate.
Heparan sulfate, an extensively sulfated glycosaminoglycan abundant on cell surface proteoglycans, regulates intercellular… (More)
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2011
2011
Lacrimal gland development and Fgf 10-Fgfr 2 b signaling is controlled by 2O and 6O sulfated heparan sulfate
Heparan sulfate (HS), an extensively sulfated glycosaminoglycan abundant on cell surface proteoglycans, regulates intercellular… (More)
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2010
2010
Sprouty2-modulated Kras signaling rescues Shp2 deficiency during lens and lacrimal gland development.
Shp2/Ptpn11 tyrosine phosphatase is a general regulator of the RTK pathways. By genetic ablation, we demonstrate that Shp2 is… (More)
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2009
2009
Purification and characterization of mouse lacrimal gland epithelial cells and reconstruction of an acinarlike structure in three-dimensional culture.
PURPOSE To clarify which factors are involved in postnatal lacrimal gland development, the expressions of several growth factors… (More)
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2007
2007
Bud specific N-sulfation of heparan sulfate regulates Shp2-dependent FGF signaling during lacrimal gland induction.
Preferential outgrowth of the bud cells forms the basis of branching morphogenesis. Here, we show that lacrimal gland development… (More)
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2006
2006
The role of the forkhead transcription factor, Foxc1, in the development of the mouse lacrimal gland.
The lacrimal gland produces secretions that lubricate and protect the cornea of the eye. Foxc1 encodes a forkhead/winged helix… (More)
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Highly Cited
2000
Highly Cited
2000
FGF10 is an inducer and Pax6 a competence factor for lacrimal gland development.
We investigated the mechanism of tissue induction and specification using the lacrimal gland as a model system. This structure… (More)
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