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jiadifenin

 
National Institutes of Health

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Sesquiterpenes

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2011
2011
Synthesis of the ABC ring system of Jiadifenin via Pd-catalyzed cyclizations.
An efficient route toward the central ABC system of jiadifenin has been developed using two key Pd-catalyzed cyclizations. A… Expand
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2006
2006
Total synthesis of (+/-)-jiadifenin and studies directed to understanding its SAR: probing mechanistic and stereochemical issues in palladium-mediated allylation of enolate-like structures.
The total synthesis of jiadifenin has been accomplished. The synthesis allows us to build an SAR profile which suggests that the… Expand
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2004
2004
Total synthesis of (+/-)-jiadifenin, a non-peptidyl neurotrophic modulator.
We report the first total synthesis of jiadifenin (1), the establishment of a modality for its biological evaluation, and the… Expand
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2002
2002
New seco-prezizaane-type sesquiterpenes, jiadifenin with neurotrophic activity and 1,2-dehydroneomajucin from Illicium jiadifengpi.
Two new seco-prezizaane-type sesquiterpenes, 1,2-dehydroneomajucin (1) and jiadifenin (2), were isolated from the methanol… Expand
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