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isometamidium

Known as: 8-(3-(M-Amidinophenyl)-2-Triazeno)-3-Amino-5-Ethyl-6-Phenylphenanthridinium, isometamidium ion, isometamidium cation 
 
National Institutes of Health

Papers overview

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2006
2006
Objective  To determine the drug resistance of Trypanosoma brucei rhodesiense strains isolated from sleeping sickness patients in… Expand
Review
2001
Review
2001
  • H. D. de Koning
  • International journal for parasitology
  • 2001
  • Corpus ID: 39851109
Sleeping sickness is an increasing problem in many parts of sub-Saharan Africa. The problems are compounded by the lack of new… Expand
1997
1997
Thirty‐six Trypanosoma brucei spp. stocks isolated from man and domestic animals in south‐east Uganda were studied for… Expand
1997
1997
Resistance to isometamidium was increased 94-fold in a clone of Trypanosoma congolense (clone IL 1180) by repeated subcurative… Expand
  • table 1
  • table 2
Highly Cited
1987
Highly Cited
1987
The drug sensitivity of seven Trypanosoma vivax-isolates from Kenya and Somalia was examined. With the exception of diminazene… Expand
Review
1986
Review
1986
Glossina infected with African trypanosomes infest 107 Km2 of intertropical Africa. Ten thousand cases of human sleeping sickness… Expand
Highly Cited
1984
Highly Cited
1984
The frequent reappearance of patent parasitemia, mainly Trypanosoma congolense, in cattle maintained under isometamidium… Expand
  • figure 1
  • table 1
1980
1980
Concentrations of isometamidium in goat tissues were examined at intervals following a single intravenous or intramuscular dose… Expand
1967
1967
Summary Isometamidium leaves the blood rapidly in rats after i.v. injection and within a few minutes most of the compound is… Expand
1960
1960
THE trypanocidal drug, metamidium, first described by Wragg, Washbourn, Brown and Hill1, was obtained from the coupling reaction… Expand