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isoguvacine

Known as: 1,2,3,6-tetrahydro-4-pyridinecarboxylic acid 
 
National Institutes of Health

Papers overview

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Highly Cited
2006
Highly Cited
2006
Several groups have characterized the pharmacology of α4- or α6β3δ-containing GABAA receptors expressed in different cell systems… Expand
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Highly Cited
2006
Highly Cited
2006
Lesion or pharmacological manipulation of the dorsolateral pons can transform the breathing pattern to apneusis (pathological… Expand
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Highly Cited
2002
Highly Cited
2002
Background This study tests the hypothesis that loss of spinal activity of &ggr;-aminobutyric acid (GABA) contributes to the… Expand
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Highly Cited
2002
Highly Cited
2002
The actions of the anticonvulsant gabapentin [1-(aminomethyl)cyclohexaneacetic acid, Neurontin] have been somewhat enigmatic… Expand
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Highly Cited
1997
Highly Cited
1997
We asked whether GABA(A) and NMDA receptors may act in synergy in neonatal hippocampal slices, at a time when GABA exerts a… Expand
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Highly Cited
1997
Highly Cited
1997
gamma-Hydroxybutyrate (GHB) has been reported to be a ligand for GABAB receptor(s), although with low or very low affinity (IC50… Expand
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Highly Cited
1983
Highly Cited
1983
1 Saturable binding of (±)‐[3H]‐baclofen and [3H]‐γ‐aminobutyric acid ([3H]‐GABA) to rat brain crude synaptic membranes has been… Expand
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Highly Cited
1981
Highly Cited
1981
The presence of a novel receptor for the neurotransmitter γ-aminobutyric acid (GABA) on peripheral autononric nerve terminals and… Expand
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Highly Cited
1978
Highly Cited
1978
Abstract— The GABA analogue, muscimol, was taken up relatively inefficiently compared to GABA by slices of rat cerebral cortex at… Expand
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Highly Cited
1977
Highly Cited
1977
COMPOUNDS which mimic the activity of the inhibitory neurotransmitter γ-aminobutyric acid (GABA) on postsynaptic receptors are of… Expand
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