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isoguvacine

Known as: 1,2,3,6-tetrahydro-4-pyridinecarboxylic acid 
National Institutes of Health

Papers overview

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Highly Cited
2006
Highly Cited
2006
Several groups have characterized the pharmacology of α4- or α6β3δ-containing GABAA receptors expressed in different cell systems… Expand
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Highly Cited
2006
Highly Cited
2006
Lesion or pharmacological manipulation of the dorsolateral pons can transform the breathing pattern to apneusis (pathological… Expand
Highly Cited
2002
Highly Cited
2002
Background This study tests the hypothesis that loss of spinal activity of &ggr;-aminobutyric acid (GABA) contributes to the… Expand
Highly Cited
2002
Highly Cited
2002
The actions of the anticonvulsant gabapentin [1-(aminomethyl)cyclohexaneacetic acid, Neurontin] have been somewhat enigmatic… Expand
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Highly Cited
1997
Highly Cited
1997
We asked whether GABA(A) and NMDA receptors may act in synergy in neonatal hippocampal slices, at a time when GABA exerts a… Expand
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Highly Cited
1997
Highly Cited
1997
gamma-Hydroxybutyrate (GHB) has been reported to be a ligand for GABAB receptor(s), although with low or very low affinity (IC50… Expand
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Highly Cited
1983
Highly Cited
1983
1 Saturable binding of (±)‐[3H]‐baclofen and [3H]‐γ‐aminobutyric acid ([3H]‐GABA) to rat brain crude synaptic membranes has been… Expand
Highly Cited
1981
Highly Cited
1981
The presence of a novel receptor for the neurotransmitter γ-aminobutyric acid (GABA) on peripheral autononric nerve terminals and… Expand
Highly Cited
1978
Highly Cited
1978
Abstract— The GABA analogue, muscimol, was taken up relatively inefficiently compared to GABA by slices of rat cerebral cortex at… Expand
Highly Cited
1977
Highly Cited
1977
COMPOUNDS which mimic the activity of the inhibitory neurotransmitter γ-aminobutyric acid (GABA) on postsynaptic receptors are of… Expand