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isobrucein B

A quassinoid phytochemical isolated from the tropical plant Cedronia granatensis with potential antineoplastic and chemopreventive activities. (NCI04… 
National Institutes of Health

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Quassins

Papers overview

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2014
2014
Gastro-protective effects of isobrucein B, a quassinoid isolated from Picrolemma sprucei.
2012
2012
Quantification of Antimalarial Quassinoids Neosergeolide and Isobrucein B in Stem and Root Infusions of Picrolemma sprucei Hook F. by HPLC-UV Analysis
Rita C. S. Nunomura1, Ellen C. C. Silva1, Sergio M. Nunomura2, Ana C. F. Amaral3, Alaide S. Barreto3, Antonio C. Siani3 and… 
2009
2009
Biological activity of neosergeolide and isobrucein B (and two semi-synthetic derivatives) isolated from the Amazonian medicinal plant Picrolemma sprucei (Simaroubaceae).
In the present study, in vitro techniques were used to investigate a range of biological activities of known natural quassinoids… 
2009
2009
LC-ESI-MS determination of quassinoids isobrucein B and neosergeolide in Picrolemma sprucei stem infusions
Infusoes dos caules de Picrolemma sprucei (pseudonimo: P. pseudocoffea) sao principalmente utilizadas como antimalaricos em toda… 
2009
2009
Gram-scale isolation of isobrucein B and neosergeolide from Picrolemma sprucei Hook. f.
Quassinoids neosergeolide and isobrucein B, obtained from Picrolemma sprucei, have proven in vitro antitumor, antimalarial… 
2007
2007
Cytotoxicity Assessment of Quassinoids Neosergeolide and Isobrucein B toward Hematopoietic and Solid Malignancies Identifies STAT3 Activation To Be Predictive of Antitumor Response.
Quassinoids are natural product compounds known to possess tumor cytotoxicity and antimalarial activity. Neosergiolide and… 
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