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isaxonine

Known as: 2-Isopropylaminopyrimidine, 2-Pyrimidinamine, N-(1-methylethyl)-, Isopropylaminopyrimidine 
 
National Institutes of Health

Papers overview

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1993
1993
From the study using cultured human and mouse neuroblastoma cells, we found that a new type of synthetic bicyclic pyrimidine… Expand
Highly Cited
1991
Highly Cited
1991
1 In rats, recovery of sensory‐motor function following a crush lesion of the sciatic or tibial nerve was monitored by measuring… Expand
1989
1989
Isaxonine and several other drugs transformed by cytochrome P‐450 into reactive metabolites apparently lead to immunoallergic… Expand
1988
1988
A randomized double‐blind therapeutic trial of isaxonine was completed over a 2‐year period for 20 ambulant boys with Duchenne… Expand
1988
1988
Abstract Adverse drug reactions may mimic almost any kind of liver disease. Acute hepatitis is often due to the formation of… Expand
Highly Cited
1985
Highly Cited
1985
A study from five hepatology units documenting 157 cases of drug‐induced hepatitis and a second study from a laboratory of… Expand
1985
1985
Administration of isaxonine (6 mg/kg powdered diet) had no effect on regeneration following sciatic nerve crush in the rat. In 10… Expand
1984
1984
The metabolism of isaxonine was first investigated in mice. Incubation, under air, of [2-14C] isaxonine (1 mM) with mouse liver… Expand
1984
1984
Coincubation of 0.4 mM [3H]glutathione with 4 mM isaxonine , an NADPH-generating system, glutathione S-transferase and mouse… Expand
1983
1983
The polymerization of tubulin leads to the formation of microtubules which are one of the components of the axons of nerve cells… Expand