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isaxonine

Known as: 2-Isopropylaminopyrimidine, 2-Pyrimidinamine, N-(1-methylethyl)-, Isopropylaminopyrimidine 
 
National Institutes of Health

Papers overview

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2005
2005
After sciatic nerve lesion by freezing, the length of the most rapidly regenerating fibres was significantly increased by i.p… Expand
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1989
1989
Isaxonine and several other drugs transformed by cytochrome P-450 into reactive metabolites apparently lead to immunoallergic… Expand
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Review
1988
Review
1988
Adverse drug reactions may mimic almost any kind of liver disease. Acute hepatitis is often due to the formation of reactive… Expand
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1988
1988
A randomized double-blind therapeutic trial of isaxonine was completed over a 2-year period for 20 ambulant boys with Duchenne… Expand
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1985
1985
A study from five hepatology units documenting 157 cases of drug-induced hepatitis and a second study from a laboratory of… Expand
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1985
1985
Administration of isaxonine (6 mg/kg powdered diet) had no effect on regeneration following sciatic nerve crush in the rat. In 10… Expand
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1985
1985
Electrophysiologic detection of the first signs of gastrocnemius muscle reinnervation shows that after a single localized… Expand
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1984
1984
The metabolism of isaxonine was first investigated in mice. Incubation, under air, of [2-14C] isaxonine (1 mM) with mouse liver… Expand
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1984
1984
Coincubation of 0.4 mM [3H]glutathione with 4 mM isaxonine , an NADPH-generating system, glutathione S-transferase and mouse… Expand
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1983
1983
The polymerization of tubulin leads to the formation of microtubules which are one of the components of the axons of nerve cells… Expand
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