iperoxo

 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2013-2017
012320132017

Papers overview

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2018
2018
The muscarinic M2 acetylcholine receptor, one of the few G-protein coupled receptors that has not only been crystallized in both… (More)
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2017
2017
Aiming to design partial agonists as well as allosteric modulators for the M1 muscarinic acetylcholine (M1AChR) receptor, two… (More)
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2017
2017
Muscarinic receptor agonists are characterized by apparently strict restraints on their tertiary or quaternary amine and their… (More)
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2015
2015
Aiming to design partial agonists for a G-protein-coupled receptor based on dynamic ligand binding, we synthesized three… (More)
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2014
2014
Activation of G protein-coupled receptors involves major conformational changes of the receptor protein ranging from the… (More)
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2014
2014
In this study, we synthesized and tested in vitro and in vivo two groups of bis(ammonio)alkane-type compounds, 6a-9a and 6b-9b… (More)
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2014
2014
The M4 receptor is a compelling therapeutic target, as this receptor modulates neural circuits dysregulated in schizophrenia, and… (More)
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2014
2014
The M(4) receptor is a compelling therapeutic target, as this receptor modulates neural circuits dysregulated in schizophrenia… (More)
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Highly Cited
2013
Highly Cited
2013
Despite recent advances in crystallography and the availability of G-protein-coupled receptor (GPCR) structures, little is known… (More)
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2013
2013
BACKGROUND AND PURPOSE Artificial agonists may have higher efficacy for receptor activation than the physiological agonist. Until… (More)
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