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iperoxo

 
National Institutes of Health

Papers overview

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2019
2019
Red-shifted azobenzene scaffolds have emerged as useful molecular photoswitches to expand potential applications of… Expand
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2018
2018
Muscarinic acetylcholine receptors are GPCRs that regulate the activity of a diverse array of central and peripheral functions in… Expand
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2018
2018
The muscarinic M2 acetylcholine receptor, one of the few G-protein coupled receptors that has not only been crystallized in both… Expand
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2017
2017
A set of hybrid compounds composed of the fragment of allosteric modulators of the muscarinic receptor, i.e. W84 and… Expand
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2016
2016
G-protein-coupled receptors (GPCRs) recognize ligands of widely different efficacies, from inverse to partial and full agonists… Expand
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2015
2015
Aiming to design partial agonists for a G-protein-coupled receptor based on dynamic ligand binding, we synthesized three… Expand
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2014
2014
In this study, we synthesized and tested in vitro and in vivo two groups of bis(ammonio)alkane-type compounds, 6a-9a and 6b-9b… Expand
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2014
2014
The M(4) receptor is a compelling therapeutic target, as this receptor modulates neural circuits dysregulated in schizophrenia… Expand
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Highly Cited
2013
Highly Cited
2013
Despite recent advances in crystallography and the availability of G-protein-coupled receptor (GPCR) structures, little is known… Expand
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2013
2013
BACKGROUND AND PURPOSE Artificial agonists may have higher efficacy for receptor activation than the physiological agonist. Until… Expand
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