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iperoxo

National Institutes of Health

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2 relations

Broader (2)

IsoxazolesQuaternary Ammonium Compounds

Papers overview

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2018
2018
Synergistic regulation mechanism of iperoxo and LY2119620 for muscarinic acetylcholine M2 receptor
Muscarinic acetylcholine receptors are GPCRs that regulate the activity of a diverse array of central and peripheral functions in… 
2018
2018
N-Ethylmaleimide differentiates between the M2- and M4-autoreceptor-mediated inhibition of acetylcholine release in the mouse brain
Muscarinic M2 and M4 receptors resemble each other in brain distribution, function, and Gi/o protein signaling. However, there is… 
2018
2018
Modelling and mathematical analysis of the M$_{2}$ receptor-dependent joint signalling and secondary messenger network in CHO cells.
The muscarinic M$_{2}$ receptor is a prominent member of the GPCR family and strongly involved in heart diseases. Recently… 
2017
2017
FRET Studies of Quinolone-Based Bitopic Ligands and Their Structural Analogues at the Muscarinic M1 Receptor.
Aiming to design partial agonists as well as allosteric modulators for the M1 muscarinic acetylcholine (M1AChR) receptor, two… 
2016
2016
Data Publication and Dissemination with the Structural Biology Data Grid
Access to experimental X-­‐‐ray diffraction image data is fundamental for validation and reproduction of… 
2014
2014
Bis(ammonio)alkane-type agonists of muscarinic acetylcholine receptors: synthesis, in vitro functional characterization, and in vivo evaluation of their analgesic activity.
2014
2014
Dualsteric activation of M2 muscarinic acetylcholine receptors inhibits cell proliferation in human glioblastoma cell lines
Muscarinic acetylcholine receptors (mAChRs) are expressed in several primary and metastatic tumours. ACh synthesized by the… 
2012
2012
Agonists with supraphysiological efficacy at the muscarinic M 2 acetylcholine receptor 1 Running title : Supraphysiological M 2 receptor activation
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