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inv(16)

A chromosomal inversion that involves chromosome 16.
National Institutes of Health

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1 relation
Chromosomes, Human, Pair 16

Papers overview

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Highly Cited
2008
Highly Cited
2008
Transcriptional repression of the RUNX3/AML2 gene by the t(8;21) and inv(16) fusion proteins in acute myeloid leukemia.
RUNX3/AML2 is a Runt domain transcription factor like RUNX1/AML1 and RUNX2/AML3. Regulated by 2 promoters P1 and P2, RUNX3 is… 
2007
2007
Utility of interphase FISH to stratify patients into cytogenetic risk categories at diagnosis of AML in an Eastern Cooperative Oncology Group (ECOG) clinical trial (E1900).
2004
2004
MmTRA1b/phospholipid scramblase 1 gene expression is a new prognostic factor for acute myelogenous leukemia.
2000
2000
Use of dual-color interphase FISH for the detection of inv(16) in acute myeloid leukemia at diagnosis, relapse and during follow-up: a study of 23 patients
The value of dual-color fluorescence in situ hybridization (FISH) for the detection of inv(16), using two contigs of cosmid… 
1999
1999
Genomic acute myeloid leukemia-associated inv(16)(p13q22) breakpoints are tightly clustered
The inv(16) and related t(16;16) are found in 10% of all cases with de novo acute myeloid leukemia. In these rearrangements the… 
1999
1999
Increased karyotype precision using fluorescence in situ hybridization and spectral karyotyping in patients with myeloid malignancies.
Highly Cited
1998
Highly Cited
1998
Detection of CBFβ/MYH11 fusion transcripts in patients with inv(16) acute myeloid leukemia after allogeneic bone marrow or peripheral blood progenitor cell transplantation
We evaluated the occurrence of the CBFβ/MYH11 fusion transcripts by PCR analysis in 10 patients with inv(16)(p13;q22) acute… 
1998
1998
Inv(16) acute myeloid leukemia cells show an increased sensitivity to cytosine arabinoside in vitro
Abstract: Karyotype represents the major independent prognostic factor for response and remission duration in acute leukemia. In… 
1996
1996
Identification of the chimeric protein product of the CBFB‐MYH11 fusion gene in inv(16) leukemia cells
An expressed gene formed by fusion between the CBFB transcription factor gene and the smooth muscle myosin heavy chain gene MYH11… 
Review
1995
Review
1995
Cytogenetic and clinical correlates in AML patients with abnormalities of chromosome 16.
Abnormalities of chromosome 16 in AML include del(16q), inv(16) and t(16;16). These three groups have been categorized together… 
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