inv(16)

A chromosomal inversion that involves chromosome 16.
National Institutes of Health

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2013
2013
The t(8;21) and inv(16) chromosomal aberrations generate the oncoproteins AML1-ETO (A-E) and CBFβ-SMMHC (C-S). The role of these… (More)
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Highly Cited
2010
Highly Cited
2010
Diagnostic karyotype provides the framework for risk-stratification schemes in acute myeloid leukemia (AML); however, the… (More)
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Highly Cited
2006
Highly Cited
2006
PURPOSE To analyze the prognostic impact of mutated KIT (mutKIT) in core-binding factor acute myeloid leukemia (AML) with inv(16… (More)
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Highly Cited
2005
Highly Cited
2005
PURPOSE Because both t(8;21) and inv(16) disrupt core binding factor (CBF) in acute myeloid leukemia (AML) and confer relatively… (More)
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Highly Cited
2004
Highly Cited
2004
BACKGROUND In patients with acute myeloid leukemia (AML) a combination of methods must be used to classify the disease, make… (More)
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Highly Cited
2003
Highly Cited
2003
Inversion(16) is one of the most frequent chromosomal translocations found in acute myeloid leukemia (AML), occurring in over 8… (More)
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Highly Cited
2002
Highly Cited
2002
FLT3 length mutation (FLT3-LM) is a molecular marker potentially useful for the characterization of acute myeloid leukemia (AML… (More)
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Highly Cited
2001
Highly Cited
2001
Acute myeloid leukemia (AML) in older adults carries a poor prognosis, and the optimum treatment remains to be determined. In… (More)
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Highly Cited
1998
Highly Cited
1998
Cytogenetics is considered one of the most valuable prognostic determinants in acute myeloid leukemia (AML). However, many… (More)
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Highly Cited
1998
Highly Cited
1998
Advances in the treatment of acute myeloid leukemia (AML) have occurred with the introduction of new therapies including high… (More)
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