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interstrand cross-link repair

Known as: ICL repair 
Removal of a DNA interstrand crosslink (a covalent attachment of DNA bases on opposite strands of the DNA) and restoration of the DNA. DNA… 
National Institutes of Health

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nucleotide-excision repair involved in interstrand cross-link repair

Papers overview

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Review
2013
Review
2013
DNA crosslinking damage and cancer - a tale of friend and foe.
Interstrand crosslinks (ICLs) represent a major challenge for DNA replication and transcription by preventing DNA strand… 
Highly Cited
2008
Highly Cited
2008
Processing of a Psoralen DNA Interstrand Cross-link by XPF-ERCC1 Complex in Vitro*
The processing of stalled forks caused by DNA interstrand cross-links (ICLs) has been proposed to be an important step in… 
Highly Cited
2007
Highly Cited
2007
DOG-1 Is the Caenorhabditis elegans BRIP1/FANCJ Homologue and Functions in Interstrand Cross-Link Repair
ABSTRACT Fanconi anemia (FA) is a cancer susceptibility syndrome characterized by defective DNA interstrand cross-link (ICL… 
Review
2007
Review
2007
Contributions of DNA interstrand cross-links to aging of cells and organisms
Impaired DNA damage repair, especially deficient transcription-coupled nucleotide excision repair, leads to segmental progeroid… 
2006
2006
Functional Interplay between BRCA2/FancD1 and FancC in DNA Repair*
A rare hereditary disorder, Fanconi anemia (FA), is caused by mutations in an array of genes, which interact in a common FA… 
Highly Cited
2004
Highly Cited
2004
The Structure-Specific Endonuclease Ercc1-Xpf Is Required To Resolve DNA Interstrand Cross-Link-Induced Double-Strand Breaks
ABSTRACT Interstrand cross-links (ICLs) are an extremely toxic class of DNA damage incurred during normal metabolism or cancer… 
Highly Cited
2004
Highly Cited
2004
DNA Cross-Link Repair Protein SNM1A Interacts with PIAS1 in Nuclear Focus Formation
ABSTRACT The yeast SNM1/PSO2 gene specifically functions in DNA interstrand cross-link (ICL) repair, and its role has been… 
Highly Cited
2000
Highly Cited
2000
Repair of an Interstrand DNA Cross-link Initiated by ERCC1-XPF Repair/Recombination Nuclease*
Interstrand DNA cross-link damage is a severe challenge to genomic integrity. Nucleotide excision repair plays some role in the… 
Highly Cited
1999
Highly Cited
1999
Interstrand Cross-Links Induce DNA Synthesis in Damaged and Undamaged Plasmids in Mammalian Cell Extracts
ABSTRACT Mammalian cell extracts have been shown to carry out damage-specific DNA repair synthesis induced by a variety of… 
Highly Cited
1997
Highly Cited
1997
Initiation of DNA interstrand cross-link repair in humans: the nucleotide excision repair system makes dual incisions 5' to the cross-linked base and removes a 22- to 28-nucleotide-long damage-free…
Most DNA repair mechanisms rely on the redundant information inherent to the duplex to remove damaged nucleotides and replace… 
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