interleukin-27 complex

Known as: IL-27 complex, p28, interleukin-27 complex location 
A protein complex that is composed of an interleukin-27p28 subunit (product of the IL27 gene) and an EBI3 subunit and is secreted into the… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1996-2018
05101519962018

Papers overview

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2009
2009
IL-27 is formed by the association of a cytokine subunit, p28, with the soluble cytokine receptor EBV-induced gene 3 (EBI3). The… (More)
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Highly Cited
2008
Highly Cited
2008
EBV-induced gene 3 (EBI3) can associate with p28 to form the heterodimeric cytokine IL-27, or with the p35 subunit of IL-12 to… (More)
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Highly Cited
2005
Highly Cited
2005
A novel cytokine interleukin-27 (IL-27), composed of p28 and Epstein-Barr virus-induced gene 3 (EBI3), is produced from activated… (More)
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Highly Cited
2005
Highly Cited
2005
BACKGROUND It has been suggested that Crohn's disease (CD) is associated with an exaggerated T-helper 1 cytokine response… (More)
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2004
Highly Cited
2004
Interleukin (IL)-27 is a newly described member of the IL-12 family. It is a heterodimeric cytokine composed of two subunits, p28… (More)
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2002
Highly Cited
2002
An efficient Th1-driven adaptive immune response requires activation of the T cell receptor and secretion of the T cell… (More)
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2002
2002
Epstein-Barr virus-induced gene 3 (EBI3) is a widely expressed IL-12p40-related protein that associates as a heterodimer with… (More)
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2001
2001
In human pregnancy, trophoblasts are the only cells of fetal origin in direct contact with the maternal immune system… (More)
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1997
Highly Cited
1997
The Epstein-Barr virus-induced gene 3 (EBI3) is a novel soluble hematopoietin component related to the p40 subunit of interleukin… (More)
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1996
Highly Cited
1996
We have isolated a cDNA encoding a novel hematopoietin receptor family member related to the p40 subunit of interleukin-12 and to… (More)
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