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interleukin-1 receptor activity

Known as: IL-1 receptor activity, IL-1R 
Combining with interleukin-1 to initiate a change in cell activity. Interleukin-1 is produced mainly by activated macrophages and is involved in the… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1989-2016
02419892016

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2 relations
Receptors, Interleukin-1

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interleukin-1 binding activity

Related mentions per year

Related mentions per year

1985-2018
19801990200020102020
interleukin-1 receptor activity
interleukin-1 binding activity
Receptors, Interleukin-1

Papers overview

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2015
2015
Identification of Potential Small Molecule Allosteric Modulator Sites on IL-1R1 Ectodomain Using Accelerated Conformational Sampling Method
The interleukin-1 receptor (IL-1R) is the founding member of the interleukin 1 receptor family which activates innate immune… (More)
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2004
2004
Learning modulation by endogenous hippocampal IL-1: blockade of endogenous IL-1 facilitates memory formation.
The interleukin-1 (IL-1) cytokine family (IL-1alpha, IL-beta, and the IL-1 receptor antagonist) is involved in immune and… (More)
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2004
2004
Tolerance induced by the lipopeptide Pam3Cys is due to ablation of IL-1R-associated kinase-1.
Stimulation of the human monocytic cell line Mono Mac 6 with the synthetic lipopeptide (S)-(2,3-bis(palmitoyloxy)-(2RS)-propyl)-N… (More)
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Highly Cited
2003
Highly Cited
2003
Phosphoinositide 3 kinase mediates Toll-like receptor 4-induced activation of NF-kappa B in endothelial cells.
Many of the proinflammatory effects of gram-negative bacteria are elicited by the interaction of bacterial lipopolysaccharide… (More)
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1999
1999
Induction of the bradykinin B2-receptor, but not of the bradykinin B1-receptor, by interleukin-1beta in cultivated human decidua-derived cells.
Aspects of the pathophysiological steps leading to preterm labor after intrauterine infection can be studied in a cell culture… (More)
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1995
1995
Interleukin-1 beta and tumour necrosis factor-alpha stimulate the mRNA expression of interleukin-1 receptors in mouse anterior pituitary AtT-20 cells.
The RT-PCR technique was used to study IL-1 receptor mRNA levels in AtT-20 cells. IL-1 beta increased type I IL-1 receptor mRNA… (More)
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1993
1993
Interleukin 1 receptor on fibroblasts from systemic sclerosis patients induces excessive functional responses to interleukin 1 beta.
To determine if SSc fibroblasts are more sensitive to exogenous IL-1 than are normal fibroblasts, we studied the inductions of IL… (More)
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1992
1992
Pattern of IL-1 receptor gene expression suggests role in noninflammatory processes.
The cytokine IL-1 can be elaborated by most nucleated cell types and exerts its pleiotropic effects on a variety of tissues… (More)
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1992
1992
Molecular characterization of the interleukin-1 receptor (IL-1R) on monocytes and polymorphonuclear cells.
Primary human monocytes and monocytic cells express an interleukin 1 receptor (IL-1R) which is similar in molecular weight and IL… (More)
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1989
1989
Contribution of IL-6 to the antiproliferative effect of IL-1 and tumor necrosis factor on tumor cell lines.
The role of IL-6 in the antiproliferative effect of IL-1 for tumor cell lines was investigated using IL-1-sensitive cell lines… (More)
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