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insulin receptor signaling pathway
Known as:
insulin receptor signalling pathway
The series of molecular signals generated as a consequence of the insulin receptor binding to insulin. [GOC:ceb]
National Institutes of Health
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insulin receptor activity
insulin receptor signaling pathway involved in dauer larval development
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Combining Bioinformatics Techniques to Study Diabetes Biomarkers and Related Molecular Mechanisms
Han Nie
,
Kaihua Zhang
,
Jiasheng Xu
,
Kaili Liao
,
Weimin Zhou
,
Z. Fu
Frontiers in Genetics
2020
Corpus ID: 216642972
Objective To explore the mechanism of plasma circulating miRNA-126 and miRNA-28-3p in diabetes mellitus (DM) patients, and to…
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Review
2019
Review
2019
[Overview on hypoglycemic active constituents of traditional Chinese medicine based on insulin receptor signaling pathway].
Huajuan Lyu
,
Meng Luo
,
Yuxia Li
,
Heng-Pei Jiang
,
Ji-zhong Yan
,
Shengqiang Tong
Zhongguo Zhong yao za zhi = Zhongguo zhongyao…
2019
Corpus ID: 209464177
Insulin resistance,as the main link in the pathogenesis of type 2 diabetes mellitus( T2 DM),runs through the whole process of…
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2016
2016
Enhanced survival of Drosophila Akt1 hypomorphs during amino-acid starvation requires foxo.
J. D. Slade
,
B. Staveley
Genome
2016
Corpus ID: 5084169
Disordered eating includes any pattern of irregular eating that may lead to either extreme weight loss or obesity. The conserved…
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2015
2015
Flavaglines Stimulate Transient Receptor Potential Melastatin Type 6 (TRPM6) Channel Activity
Maxime G. Blanchard
,
J. D. de Baaij
,
+6 authors
J. Hoenderop
PLoS ONE
2015
Corpus ID: 215221592
Magnesium (Mg2+) is essential for enzymatic activity, brain function and muscle contraction. Blood Mg2+ concentrations are…
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2014
2014
Extra-nuclear activity of INSM1 transcription factor enhances insulin receptor signaling pathway and Nkx6.1 expression through RACK1 interaction.
Tao Zhang
,
Chiachen Chen
,
M. Breslin
,
K. Song
,
M. Lan
Cellular Signalling
2014
Corpus ID: 8146837
2013
2013
UP780, a Chromone-Enriched Aloe Composition, Enhances Adipose Insulin Receptor Signaling and Decreases Liver Lipid Biosynthesis
J. Tseng-Crank
,
Seon‐Gil Do
,
+5 authors
Q. Jia
2013
Corpus ID: 19243277
Nutrigenomic studies were conducted to uncover the mechanism of action for the hypoglycemic and insulin sensitizing effects of…
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2012
2012
Heparanase Enhances the Insulin Receptor Signaling Pathway to Activate Extracellular Signal-regulated Kinase in Multiple Myeloma*
Anurag Purushothaman
,
S. Babitz
,
R. Sanderson
Journal of Biological Chemistry
2012
Corpus ID: 23811418
Background: ERK phosphorylation is enhanced by heparanase, an enzyme associated with aggressive behavior of multiple myeloma…
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2012
2012
A new recombinant pituitary adenylate cyclase-activating peptide-derived peptide efficiently promotes glucose uptake and glucose-dependent insulin secretion.
Yi Ma
,
Tianjie Luo
,
Wenna Xu
,
Zulu Ye
,
An Hong
Acta Biochimica et Biophysica Sinica
2012
Corpus ID: 55754
The recombinant peptide, DBAYL, a promising therapeutic peptide for type 2 diabetes, is a new, potent, and highly selective…
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2002
2002
A gain-of-function screen to identify novel components of the insulin receptor signalling pathway and other growth regulators in Drosophila melanogaster.
F. Re
2002
Corpus ID: 113753295
1999
1999
Insulin receptor substrate 1-induced inhibition of endoplasmic reticulum Ca2+ uptake in beta-cells. Autocrine regulation of intracellular ca2+ homeostasis and insulin secretion.
G. Xu
,
Z. Gao
,
P. D. Borge
,
B. Wolf
Journal of Biological Chemistry
1999
Corpus ID: 6817454
To understand the role of the insulin receptor pathway in beta-cell function, we have generated stable beta-cells (betaIRS1-A…
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