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insulin receptor signaling pathway

Known as: insulin receptor signalling pathway 
The series of molecular signals generated as a consequence of the insulin receptor binding to insulin. [GOC:ceb]
National Institutes of Health

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insulin receptor activityinsulin receptor signaling pathway involved in dauer larval development

Papers overview

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2019
2019
Combination of Insulin with a GLP1 Agonist Is Associated with Better Memory and Normal Expression of Insulin Receptor Pathway Genes in a Mouse Model of Alzheimer’s Disease
Disruption of brain insulin signaling may explain the higher Alzheimer’s disease (AD) risk among type 2 diabetic (T2D) patients… Expand
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2018
2018
Parahippocampal gyrus expression of endothelial and insulin receptor signaling pathway genes is modulated by Alzheimer’s disease and normalized by treatment with anti-diabetic agents
A large body of literature links risk of cognitive decline, mild cognitive impairment (MCI) and dementia with Type 2 Diabetes… Expand
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2014
2014
Extra-nuclear activity of INSM1 transcription factor enhances insulin receptor signaling pathway and Nkx6.1 expression through RACK1 interaction.
INSM1 is an islet transcription factor essential for pancreas development. INSM1 functions as a transcriptional repressor of… Expand
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Review
2014
Review
2014
Ageing, adipose tissue, fatty acids and inflammation
Abstract A common feature of ageing is the alteration in tissue distribution and composition, with a shift in fat away from lower… Expand
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2012
2012
Heparanase Enhances the Insulin Receptor Signaling Pathway to Activate Extracellular Signal-regulated Kinase in Multiple Myeloma*
Background: ERK phosphorylation is enhanced by heparanase, an enzyme associated with aggressive behavior of multiple myeloma… Expand
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2012
2012
HMGA1 is a novel downstream nuclear target of the insulin receptor signaling pathway
High-mobility group AT-hook 1 (HMGA1) protein is an important nuclear factor that activates gene transcription by binding to AT… Expand
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2011
2011
Effects of Steaming Time and Frequency for Manufactured Red Liriope platyphylla on the Insulin Secretion Ability and Insulin Receptor Signaling Pathway
In oriental medicine, Liriope platyphylla (LP) has long been regarded as a curative herb useful for the treatment of diabetes… Expand
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2010
2010
Mechanisms Underlying Insulin Resistance in Human Pregnancy and Gestational Diabetes Mellitus
Obesity and pregnancy are associated with a combination of insulin resistance and inflammatory changes that exacerbate, in… Expand
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2004
2004
Pharmacological regulation of the insulin receptor signaling pathway mimics insulin action in cells transduced with viral vectors.
Diabetes mellitus derives from either insulin deficiency (type I) or resistance (type II). Homozygous mutations in the insulin… Expand
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2001
2001
Insulin inhibits leptin receptor signalling in HEK293 cells at the level of janus kinase-2: a potential mechanism for hyperinsulinaemia-associated leptin resistance
Abstract.Aims/hypothesis: Leptin resistance in obese humans seems to be predominantly caused by signalling abnormalities at the… Expand
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