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insulin receptor signaling pathway

Known as: insulin receptor signalling pathway 
The series of molecular signals generated as a consequence of the insulin receptor binding to insulin. [GOC:ceb]
National Institutes of Health

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insulin receptor activityinsulin receptor signaling pathway involved in dauer larval development

Papers overview

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2020
2020
Combining Bioinformatics Techniques to Study Diabetes Biomarkers and Related Molecular Mechanisms
Objective To explore the mechanism of plasma circulating miRNA-126 and miRNA-28-3p in diabetes mellitus (DM) patients, and to… 
Review
2019
Review
2019
[Overview on hypoglycemic active constituents of traditional Chinese medicine based on insulin receptor signaling pathway].
Insulin resistance,as the main link in the pathogenesis of type 2 diabetes mellitus( T2 DM),runs through the whole process of… 
2016
2016
Enhanced survival of Drosophila Akt1 hypomorphs during amino-acid starvation requires foxo.
Disordered eating includes any pattern of irregular eating that may lead to either extreme weight loss or obesity. The conserved… 
2015
2015
Flavaglines Stimulate Transient Receptor Potential Melastatin Type 6 (TRPM6) Channel Activity
Magnesium (Mg2+) is essential for enzymatic activity, brain function and muscle contraction. Blood Mg2+ concentrations are… 
2014
2014
Extra-nuclear activity of INSM1 transcription factor enhances insulin receptor signaling pathway and Nkx6.1 expression through RACK1 interaction.
2013
2013
UP780, a Chromone-Enriched Aloe Composition, Enhances Adipose Insulin Receptor Signaling and Decreases Liver Lipid Biosynthesis
Nutrigenomic studies were conducted to uncover the mechanism of action for the hypoglycemic and insulin sensitizing effects of… 
2012
2012
Heparanase Enhances the Insulin Receptor Signaling Pathway to Activate Extracellular Signal-regulated Kinase in Multiple Myeloma*
Background: ERK phosphorylation is enhanced by heparanase, an enzyme associated with aggressive behavior of multiple myeloma… 
2012
2012
A new recombinant pituitary adenylate cyclase-activating peptide-derived peptide efficiently promotes glucose uptake and glucose-dependent insulin secretion.
The recombinant peptide, DBAYL, a promising therapeutic peptide for type 2 diabetes, is a new, potent, and highly selective… 
2002
2002
A gain-of-function screen to identify novel components of the insulin receptor signalling pathway and other growth regulators in Drosophila melanogaster.
  • F. Re
  • 2002
  • Corpus ID: 113753295
1999
1999
Insulin receptor substrate 1-induced inhibition of endoplasmic reticulum Ca2+ uptake in beta-cells. Autocrine regulation of intracellular ca2+ homeostasis and insulin secretion.
To understand the role of the insulin receptor pathway in beta-cell function, we have generated stable beta-cells (betaIRS1-A… 
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