insulin receptor activity
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Type 2 diabetes follows a well-defined progressive pathogenesis, beginning with insulin resistance in metabolic tissues such as… Expand Background/aims The aim of this study was to assess the effect of functional ENPP1(ectoenzyme nucleotide pyrophosphate… Expand The action of insulin in a target cell begins with binding of its molecule to insulin receptors (IR), located on the outer… Expand The insulin-like growth factor-1 receptor (IGF-1R) is crucial for many functions in neoplastic cells, for example, antiapoptosis… Expand Gangliosides are known as modulators of transmembrane signaling by regulating various receptor functions. We have found that… Expand BACKGROUND
Altered regulation of signaling pathways may contribute to the pathogenesis of renal disease. We examined renal… Expand Using a standard radio-receptor assay, we have demonstrated that [125I]insulin can bind specifically to each of two types of… Expand Incubation of human erythrocyte membrane with low concentration of prostaglandin E1 or prostacyclin increased the binding of 125I… Expand : A study was made of the effect of experimental hyperinsulinemia, caused by daily administration of the increasing doses of a… Expand A study was made of the effect of experimental hyperinsulinemia, caused by daily administration of the increasing doses of a… Expand