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insulin receptor activity

Known as: insulin-activated receptor activity 
Combining with insulin and transmitting the signal across the plasma membrane to initiate a change in cell activity. [ISBN:0198506732]
National Institutes of Health

Papers overview

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2016
2016
Type 2 diabetes follows a well-defined progressive pathogenesis, beginning with insulin resistance in metabolic tissues such as… Expand
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Highly Cited
2010
Highly Cited
2010
BACKGROUND/AIMS The aim of this study was to assess the effect of functional ENPP1(ectoenzyme nucleotide pyrophosphate… Expand
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Highly Cited
2004
Highly Cited
2004
The insulin-like growth factor-1 receptor (IGF-1R) is crucial for many functions in neoplastic cells, for example, antiapoptosis… Expand
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Highly Cited
2002
Highly Cited
2002
Gangliosides are known as modulators of transmembrane signaling by regulating various receptor functions. We have found that… Expand
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Highly Cited
2001
Highly Cited
2001
BACKGROUND Altered regulation of signaling pathways may contribute to the pathogenesis of renal disease. We examined renal… Expand
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1988
1988
Using a standard radio-receptor assay, we have demonstrated that [125I]insulin can bind specifically to each of two types of… Expand
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1986
1986
Incubation of human erythrocyte membrane with low concentration of prostaglandin E1 or prostacyclin increased the binding of 125I… Expand
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1982
1982
A study was made of the effect of experimental hyperinsulinemia, caused by daily administration of the increasing doses of a… Expand
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1982
1982
The action of insulin in a target cell begins with binding of its molecule to insulin receptors (IR), located on the outer… Expand
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