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insulin processing

The formation of mature insulin by proteolysis of the precursor preproinsulin. The signal sequence is first cleaved from preproinsulin to form… 
National Institutes of Health

Papers overview

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2002
2002
Pdx1 Targets Genes Implicated in Insulin Processing and Secretion
1987
1987
Intracellular insulin processing is altered in monocytes from patients with type II diabetes mellitus.
We studied total cell-associated A14-[125I]insulin radioactivity (including surface-bound and internalized radioactivity… 
1986
1986
Insulin processing by cultured hepatocytes.
The chloroquine-sensitive and chloroquine-insensitive steps in insulin degradation by cultured hepatocytes have been explored by… 
1986
1986
Cell Type-Specific Variability of Bacitracin's Effects on Insulin Binding and Intracellular Accumulation
Bacitracin is known to inhibit proteolytic degradation of insulin and several other peptide hormones. Previous work with isolated… 
1984
1984
Insulin Processing and Dissociation - Effect of Temperature and Lysosomotropic Agents
Dissociation of intact and degraded insulin from hepatocytes in monolayer culture was examined under conditions in which… 
1982
1982
Evidence for a direct effect of bacitracin on cell-mediated insulin degradation in isolated hepatocytes.
In freshly isolated hepatocytes, in which extracellular degradation of insulin was very low, the degradation velocity was first… 
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