insulin binding

Interacting selectively and non-covalently with insulin, a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1951-2018
05010015019512017

Papers overview

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Highly Cited
2013
Highly Cited
2013
Insulin receptor signalling has a central role in mammalian biology, regulating cellular metabolism, growth, division… (More)
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Highly Cited
2002
Highly Cited
2002
The amyloid-beta (Abeta) peptide is neurotoxic and associated with the pathology of Alzheimer's disease (AD). We investigated the… (More)
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Highly Cited
1993
Highly Cited
1993
Tumor necrosis factor-alpha (TNF) has recently been shown to induce insulin resistance. We have examined the possible effect of… (More)
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Highly Cited
1992
Highly Cited
1992
Insulin rapidly stimulates tyrosine phosphorylation of a protein of approximately 185 kD in most cell types. This protein, termed… (More)
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Highly Cited
1990
Highly Cited
1990
The effect of free fatty acids (FFAs) on insulin binding and action was investigated in isolated rat hepatocytes. Oleic acid (0.4… (More)
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Highly Cited
1988
Highly Cited
1988
Pregnancy is associated with insulin resistance. We studied insulin binding and postbinding function in isolated adipocytes from… (More)
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Highly Cited
1985
Highly Cited
1985
We have studied the effects of 3 wk of continuous subcutaneous insulin infusion (CSII) on endogenous insulin secretion and action… (More)
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Highly Cited
1982
Highly Cited
1982
The present studies were undertaken to assess the mechanisms responsible for cortisol-induced insulin resistance in man. The… (More)
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Highly Cited
1978
Highly Cited
1978
Green and Kehinde (Green, H., and Kehinde, 0. (1974) Cell 1, 113-116; (1975) Cell 5, 19-27; (1976) Cell 7, 105-113) isolated and… (More)
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Highly Cited
1976
Highly Cited
1976
In six patients with acanthosis nigricans variable degrees of glucose intolerance, hyperinsulinemia and marked resistance to… (More)
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