inositol biosynthetic process

Known as: vitamin Bh biosynthetic process, inositol formation, vitamin Bh biosynthesis 
The chemical reactions and pathways resulting in the formation of inositol, 1,2,3,4,5,6-cyclohexanehexol, a growth factor for animals and… (More)
National Institutes of Health

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negative regulation of inositol biosynthetic processpositive regulation of inositol biosynthetic process

Papers overview

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Highly Cited
2014
Highly Cited
2014
Clinical whole-genome sequencing in severe early-onset epilepsy reveals new genes and improves molecular diagnosis
In severe early-onset epilepsy, precise clinical and molecular genetic diagnosis is complex, as many metabolic and electro… (More)
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2004
2004
Valproate decreases inositol biosynthesis
BACKGROUND Lithium and valproate (VPA) are used for treating bipolar disorder. The mechanism of mood stabilization has not been… (More)
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2002
2002
Restoration of silencing in Saccharomyces cerevisiae by tethering of a novel Sir2-interacting protein, Esc8.
We previously described two classes of SIR2 mutations specifically defective in either telomeric/HM silencing (class I) or rDNA… (More)
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2001
2001
Lithium and valproate decrease inositol mass and increase expression of the yeast INO1 and INO2 genes for inositol biosynthesis.
Bipolar affective disorder (manic-depressive illness) is a chronic, severe, debilitating illness affecting 1-2% of the population… (More)
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Highly Cited
1998
Highly Cited
1998
Regulation of cell-specific inositol metabolism and transport in plant salinity tolerance.
myo-Inositol and its derivatives are commonly studied with respect to cell signaling and membrane biogenesis, but they also… (More)
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1995
1995
Diabetic neuropathy in the rat: 1. Alcar augments the reduced levels and axoplasmic transport of substance P.
This study examined the sciatic nerve axonal transport of substance P-like immunoreactivity (SPLI) and its basal content in… (More)
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Highly Cited
1993
Highly Cited
1993
SAC1p is an integral membrane protein that influences the cellular requirement for phospholipid transfer protein function and inositol in yeast
Mutations in the SAC1 gene exhibit allele-specific genetic interactions with yeast actin structural gene defects and effect a… (More)
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Highly Cited
1992
Highly Cited
1992
IRE1 encodes a putative protein kinase containing a membrane-spanning domain and is required for inositol phototrophy in Saccharomyces cerevisiae.
A novel gene, IRE1, of Saccharomyces cerevisiae was cloned through genetic complementation of a myoinositol auxotrophic mutant… (More)
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1989
1989
Mutations in the Saccharomyces cerevisiae opi3 gene: effects on phospholipid methylation, growth and cross-pathway regulation of inositol synthesis.
We report the isolation of two new opi3 mutants by EMS mutagenesis, and construction of an insertion allele in vitro using the… (More)
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1976
1976
Control of inositol biosynthesis in Saccharomyces cerevisiae: properties of a repressible enzyme system in extracts of wild-type (Ino+) cells.
Inositol biosynthesis was studied in soluble, cell extracts of a wild-type (Ino) strain of Saccharomyces cerevisiae. Two… (More)
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