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inositol biosynthetic process

Known as: vitamin Bh biosynthetic process, inositol formation, vitamin Bh biosynthesis 
The chemical reactions and pathways resulting in the formation of inositol, 1,2,3,4,5,6-cyclohexanehexol, a growth factor for animals and… Expand
National Institutes of Health

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3 relations
negative regulation of inositol biosynthetic processpositive regulation of inositol biosynthetic processregulation of inositol biosynthetic process

Papers overview

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Highly Cited
2014
Highly Cited
2014
Clinical whole-genome sequencing in severe early-onset epilepsy reveals new genes and improves molecular diagnosis
In severe early-onset epilepsy, precise clinical and molecular genetic diagnosis is complex, as many metabolic and electro… Expand
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Highly Cited
2010
Highly Cited
2010
The Arabidopsis thaliana Myo-Inositol 1-Phosphate Synthase1 Gene Is Required for Myo-inositol Synthesis and Suppression of Cell Death[W]
This work uses functional genomics to delineate the role of the inositol synthesis genes in regulating growth, development, and… Expand
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Review
2000
Review
2000
Dissecting and manipulating the pathway for glycosylphos-phatidylinositol-anchor biosynthesis.
The pathway for glycosylphosphatidylinositol-anchor biosynthesis consists of at least 10 reaction steps. Many of the genes… Expand
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Highly Cited
1999
Highly Cited
1999
Temporal and spatial patterns of accumulation of the transcript of Myo-inositol-1-phosphate synthase and phytin-containing particles during seed development in rice.
Myo-inositol-1-phosphate (I[1]P) synthase (EC 5.5.1.4) catalyzes the reaction from glucose 6-phosphate to I(1)P, the first step… Expand
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Highly Cited
1998
Highly Cited
1998
Regulation of Cell-Specific Inositol Metabolism and Transport in Plant Salinity Tolerance
myo-Inositol and its derivatives are commonly studied with respect to cell signaling and membrane biogenesis, but they also… Expand
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Highly Cited
1993
Highly Cited
1993
SAC1p is an integral membrane protein that influences the cellular requirement for phospholipid transfer protein function and inositol in yeast
Mutations in the SAC1 gene exhibit allele-specific genetic interactions with yeast actin structural gene defects and effect a… Expand
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Highly Cited
1992
Highly Cited
1992
IRE1 encodes a putative protein kinase containing a membrane‐spanning domain and is required for inositol phototrophy in Saccharomyces cerevisiae
A novel gene, IRE1, of Saccharomyces cerevisiae was cloned through genetic complementation of a myo‐ inositol auxotrophic mutant… Expand
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Highly Cited
1989
Highly Cited
1989
Mutations in the Saccharomyces cerevisiae opi3 gene: effects on phospholipid methylation, growth and cross-pathway regulation of inositol synthesis.
We report the isolation of two new opi3 mutants by EMS mutagenesis, and construction of an insertion allele in vitro using the… Expand
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Highly Cited
1988
Highly Cited
1988
Saccharomyces cerevisiae cho2 mutants are deficient in phospholipid methylation and cross-pathway regulation of inositol synthesis.
Five allelic Saccharomyces cerevisiae mutants deficient in the methylation of phosphatidylethanolamine (PE) have been isolated… Expand
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Highly Cited
1963
Highly Cited
1963
THE BIOSYNTHESIS OF FREE AND PHOSPHATIDE MYO-INOSITOL FROM GLUCOSE BY MAMMALIAN TISSUE SLICES.
The abiity of the mammalian organism to carry out the conversion of D-ghlCOSC to myo-inositoll has been established in recent… Expand
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