Skip to search formSkip to main contentSkip to account menu

negative regulation of inositol biosynthetic process

Known as: negative regulation of inositol formation, down-regulation of inositol formation, downregulation of vitamin Bh biosynthetic process 
Any process that stops, prevents or reduces the frequency, rate or extent of inositol biosynthetic process. [GOC:TermGenie, PMID:22307851]
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

biological control
inositol biosynthetic process

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
Phosphorylated K-Ras limits cell survival by blocking Bcl-xL sensitization of inositol trisphosphate receptors
Significance K-Ras is mutated more often than any other oncogene, making the protein and the pathways it regulates attractive… 
Highly Cited
2000
Highly Cited
2000
The Inositol Polyphosphate 5-Phosphatases and the Apurinic/Apyrimidinic Base Excision Repair Endonucleases Share a Common Mechanism for Catalysis*
Inositol polyphosphate 5-phosphatases (5-phosphatase) hydrolyze the 5-position phosphate from the inositol ring of… 
Highly Cited
1999
Highly Cited
1999
A Conserved Inositol Phospholipid Binding Site within the Pleckstrin Homology Domain of the Gab1 Docking Protein Is Required for Epithelial Morphogenesis*
Stimulation of the hepatocyte growth factor receptor tyrosine kinase, Met, induces the inherent morphogenic program of epithelial… 
Highly Cited
1997
Highly Cited
1997
Co-ligation of the Antigen and Fc Receptors Gives Rise to the Selective Modulation of Intracellular Signaling in B Cells
Cross-linking of the Fc receptor (FcR) to surface immunoglobulin (sIg) on B cells inhibits the influx of extracellular calcium… 
Highly Cited
1989
Highly Cited
1989
Tachykinin Receptors of the NK1 Type (Substance P) Coupled Positively to Phospholipase C on Cortical Astrocytes from the Newborn Mouse in Primary Culture
Abstract: Specific 125I‐Bolton‐Hunter substance P (125I‐BHSP) binding sites are present on intact cortical astrocytes of the… 
Highly Cited
1988
Highly Cited
1988
Multiple pathways of inositol polyphosphate metabolism in angiotensin-stimulated adrenal glomerulosa cells.
Highly Cited
1987
Highly Cited
1987
Metabolism of D-myo-inositol 1,3,4,5-tetrakisphosphate by rat liver, including the synthesis of a novel isomer of myo-inositol tetrakisphosphate.
1. We have studied the metabolism of Ins(1,3,4,5)P4 (inositol 1,3,4,5-tetrakisphosphate) by rat liver homogenates incubated in a… 
Highly Cited
1986
Highly Cited
1986
Direct evidence for involvement of a guanine nucleotide-binding protein in chemotactic peptide-stimulated formation of inositol bisphosphate and trisphosphate in differentiated human leukemic (HL-60…
Highly Cited
1985
Highly Cited
1985
Pertussis toxin inhibits chemotactic peptide-stimulated generation of inositol phosphates and lysosomal enzyme secretion in human leukemic (HL-60) cells.
The binding of the chemotactic peptide N-formyl-methionyl-leucyl-phenylalanine to its cell surface receptor rapidly elicits the… 
Highly Cited
1949
Highly Cited
1949
Complete fractionation of brain cephalin; isolation from it of phosphatidyl serine, phosphatidyl ethanolamine, and diphosphoinositide.
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)