indolmycin

Known as: 5-(1-(1H-indol-3-yl)ethyl)-2-(methylamino)- 4(5H)-oxazolone 
 
National Institutes of Health

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2016
2016
Indolmycin is a natural tryptophan analog that competes with tryptophan for binding to tryptophanyl-tRNA synthetase (TrpRS… (More)
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2015
2015
The bacterial tryptophanyl-tRNA synthetase inhibitor indolmycin features a unique oxazolinone heterocycle whose biogenetic… (More)
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2009
2009
Indolmycin, a potential antibacterial drug, competitively inhibits bacterial tryptophanyl-tRNA synthetases. An effort to identify… (More)
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2004
2004
OBJECTIVES We sought to investigate the anti-staphylococcal activity of indolmycin, with particular emphasis on comparing its… (More)
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2002
2002
Aminoacyl-tRNA synthetases, a family of enzymes essential for protein synthesis, are promising targets of antimicrobials… (More)
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1983
1983
Escherichia coli cells harboring a non-attenuated trp-lac operon fusion were used to evaluate the effects of indolmycin on the… (More)
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1981
1981
Tryptophan in a concentration of 0.4 microgram/ml increased the production of indolmycin by 37%. The lipophilic character of… (More)
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1980
1980
The antimicrobial activity of indolmycin correlates with the generation time of the investigated strains. Thus, in Staphylococcus… (More)
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1979
1979
When compared with other tryptophan analogues, indolmycin is a potent inhibitor of tryptophan pyrrolase and tryptophan… (More)
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1976
1976
Indolmycin specifically prevents the formation of tryptophanyl-tRNA in a prokaryotic system in vitro using Escherichia coli… (More)
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