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indole biosynthetic process

Known as: indole formation, indole anabolism, indole biosynthesis 
The chemical reactions and pathways resulting in the formation of indole (2,3-benzopyrrole), the basis of many biologically active substances (e.g… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
Indole synthesis – something old, something new
Indoles, both naturally occurring and synthetic, exhibit wide-ranging biological activity. Unusual and complex molecular… Expand
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Highly Cited
2013
Highly Cited
2013
Rhodium(III)-catalyzed indole synthesis using N-N bond as an internal oxidant.
We report herein a Rh(III)-catalyzed cyclization of N-nitrosoanilines with alkynes for streamlined synthesis of indoles. The… Expand
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Highly Cited
2013
Highly Cited
2013
Indole synthesis by rhodium(III)-catalyzed hydrazine-directed C-H activation: redox-neutral and traceless by N-N bond cleavage.
Fishing for complements! There is an alternative to the useful Fischer indole synthesis. The new method utilizes the same… Expand
Highly Cited
2012
Highly Cited
2012
Palladium-catalyzed aerobic oxidative cyclization of N-aryl imines: indole synthesis from anilines and ketones.
We report here an operationally simple, palladium-catalyzed cyclization reaction of N-aryl imines, affording indoles via the… Expand
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Highly Cited
2010
Highly Cited
2010
Mechanistically driven development of iridium catalysts for asymmetric allylic substitution.
Enantioselective allylic substitution reactions comprise some of the most versatile methods for preparing enantiomerically… Expand
Highly Cited
2008
Highly Cited
2008
Palladium-catalyzed oxidative cyclization of N-aryl enamines: from anilines to indoles.
The indole unit is one of the most abundant and relevant heterocycles in natural products and pharmaceuticals. Despite the… Expand
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Review
2007
Review
2007
Organometallic methods for the synthesis and functionalization of azaindoles.
Azaindoles (also called pyrrolopyridines) constitute essential subunits in many pharmaceutically important compounds. The… Expand
Highly Cited
2007
Highly Cited
2007
Enterohemorrhagic Escherichia coli Biofilms Are Inhibited by 7-Hydroxyindole and Stimulated by Isatin
ABSTRACT Since indole is present at up to 500 μM in the stationary phase and is an interspecies biofilm signal (J. Lee, A… Expand
Highly Cited
2005
Highly Cited
2005
Synthesis and functionalization of indoles through palladium-catalyzed reactions.
The substituted indole nucleus [indole is the acronym from indigo (the natural dye) and oleum (used for the isolation)] is a… Expand
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Highly Cited
2005
Highly Cited
2005
O-Acetylation of cellulose and monosaccharides using a zinc based ionic liquid
The efficient O-acetylation of monosaccharides and cellulose is demonstrated using a Lewis acidic ionic liquid based on choline… Expand
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