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indibulin

Known as: N-(Pyridin-4-yl)-(1-(4-chlorobenzyl)indol-3-yl)glycoxylamide, N-(pyridin-4-yl)-(1-(4-chlorobenzyl)indol-3-yl)glyoxylamide 
A synthetic small molecule with antimitotic and potential antineoplastic activities. Indibulin binds to a site on tubulin that is different from… Expand
National Institutes of Health

Papers overview

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2019
2019
The 1,2-dicarbonyl motif is vital to biomolecules, especially natural products and pharmaceuticals. Conventionally, 1,2… Expand
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2018
2018
Indibulin, a synthetic inhibitor of tubulin assembly, has shown promising anticancer activity with a minimal neurotoxicity in… Expand
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2016
2016
2565 Background: Indibulin (ZIO-301/D-24851) (N-(pyridin-4-yl)-[1-(4-chlorbenzyl)-indol-3-yl]-glyoxyl-amid) a novel, oral… Expand
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2012
2012
Colchicine, podophylotoxin, and indibulin are natural cytostatics that are used in the treatment of neoplasms. However… Expand
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2012
2012
Background: Indibulin (ZI0-301) is a novel, oral, synthetic small molecule microtubule inhibitor which binds tubulin at a… Expand
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Highly Cited
2009
Highly Cited
2009
Microtubule inhibitors interfere with microtubule dynamics, causing cell cycle arrest and apoptosis. These effects are… Expand
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2009
2009
SummaryIndibulin (ZIO-301/D-24851) is an orally applied small molecule with antitumor activity based upon destabilization of… Expand
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2009
2009
2538 Background: Indibulin (IDB) is a novel, orally available tubulin-targeting molecule that perturbs cancer cell migration and… Expand
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2008
2008
A series of novel podophyllotoxin derivatives were designed using association strategy and synthesized by coupling either… Expand
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2006
2006
SummaryIndibulin is a synthetic small molecule which antitumor activity is based upon destabilization of microtubules. The… Expand
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