imiquimod

Known as: 4-Amino-1-isobutyl-1H-imidazo(4,5-c)quinoline, imiquimod [Chemical/Ingredient], Imiquimodum 
A synthetic agent with immune response modifying activity. As an immune response modifier (IRM), imiquimod stimulates cytokine production, especially… (More)
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
Imiquimod is a synthetic compound with antitumor properties; a 5% cream formulation is successfully used to treat skin tumors… (More)
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Highly Cited
2012
Highly Cited
2012
Psoriasis is a common chronic autoimmune skin disease of unknown cause that involves dysregulated interplay between immune cells… (More)
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Highly Cited
2009
Highly Cited
2009
Topical application of imiquimod (IMQ), a TLR7/8 ligand and potent immune activator, can induce and exacerbate psoriasis, a… (More)
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Review
2007
Review
2007
OBJECTIVE Since imiquimod, a nucleoside analogue of the imidazoquinoline family, has shown efficacy against many tumour entities… (More)
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Highly Cited
2006
Highly Cited
2006
Immunotherapy represents an appealing option to specifically target CNS tumors using the immune system. In this report, we tested… (More)
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Highly Cited
2004
Highly Cited
2004
BACKGROUND It has been proposed that the innate immune system plays a central role in driving the autoimmune T-cell cascade… (More)
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Highly Cited
2004
Highly Cited
2004
BACKGROUND Imiquimod is an immune response modifier that is a Toll-like receptor 7 agonist that induces interferon and other… (More)
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Highly Cited
2002
Highly Cited
2002
The imidazoquinoline compounds imiquimod and R-848 are low-molecular-weight immune response modifiers that can induce the… (More)
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Review
2002
Review
2002
A central development of the past decade has been in our understanding of the interactions between, and interdependence of, the… (More)
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Highly Cited
1995
Highly Cited
1995
Imiquimod (R-837, S-26308) and the analogue S-27609 were evaluated for cytokine induction in human blood cells. Both compounds… (More)
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