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imidaprilat

Known as: 3-(2-(N-(1-carboxy-3-phenylpropyl)amino)propionyl)-1-methyl-2-oxoimidazolidine-4-carboxylic acid 
An angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. Imidaprilat competitively binds to and inhibits ACE, thereby… 
National Institutes of Health

Related topics

Related topics

2 relations

Narrower (1)

6366A

Broader (1)

Imidazolidines

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Down-regulation of carboxylesterases 1 and 2 plays an important role in prodrug metabolism in immunological liver injury rats.
2011
2011
Hepatocyte growth factor promotes an anti-inflammatory cytokine profile in human abdominal aortic aneurysm tissue.
Highly Cited
2009
Highly Cited
2009
Different Inhibitory Effects in Rat and Human Carboxylesterases
In vitro inhibition studies on drug-metabolizing enzyme activity are useful for understanding drug-drug interactions and for drug… 
Highly Cited
2007
Highly Cited
2007
(Pro)Renin Receptor–Mediated Activation of Mitogen-Activated Protein Kinases in Human Vascular Smooth Muscle Cells
Blockade of (pro)renin receptor has benefits in diabetic angiotensin II type-1a-receptor–deficient mice, suggesting the… 
2006
2006
Angiotensin II directly inhibits protein synthesis in murine myotubes.
Review
2004
Review
2004
Pharmacokinetics and pharmacokinetic/pharmacodynamic relationships for angiotensin-converting enzyme inhibitors.
The pharmacokinetic (PK) properties and the pharmacokinetic/pharmacodynamic (PK/PD) relationships for the angiotensin-converting… 
Review
2002
Review
2002
Clinical Pharmacokinetics and Selective Pharmacodynamics of New Angiotensin Converting Enzyme Inhibitors
The angiotensin converting enzyme (ACE) inhibitors are widely used in the management of essential hypertension, stable chronic… 
2000
2000
Force-length relationship in dogs as a measure of protective effect of imidapril on regional myocardial ischemia and reperfusion injury.
1997
1997
Role of kinin and renal ANG II blockade in acute effects of ACE inhibitors in low-renin hypertension.
In conscious deoxycorticosterone acetate (DOCA) salt-hypertensive dogs, the angiotensin-converting enzyme (ACE) inhibitors… 
1996
1996
Studies on the Magnitude and the Mechanism of Cough Potentiation by Angiotensin‐Converting Enzyme Inhibitors in Guinea‐pigs: Involvement of Bradykinin in the Potentiation
One adverse effect of the angiotensin‐converting enzyme (ACE) inhibitors used for treatment of hypertension and congestive heart… 
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