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hyperosmotic response

Known as: HOG response, hypertonic response, response to hypertonicity 
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene… 
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
Phospholipase Dα3 Is Involved in the Hyperosmotic Response in Arabidopsis
Rapid activation of phospholipase D (PLD), which hydrolyzes membrane lipids to generate phosphatidic acid (PA), occurs under… 
Review
2004
Review
2004
MAP kinases and the adaptive response to hypertonicity: functional preservation from yeast to mammals.
The adaptation to hypertonicity in mammalian cells is driven by multiple signaling pathways that include p38 kinase, Fyn, the… 
Review
2001
Review
2001
Physiological regulation of cyclooxygenase-2 in the kidney.
In adult mammalian kidney, cyclooxygenase-2 (COX-2) expression is found in a restricted subpopulation of cells. The two sites of… 
Highly Cited
2001
Highly Cited
2001
Salivary Acinar Cells from Aquaporin 5-deficient Mice Have Decreased Membrane Water Permeability and Altered Cell Volume Regulation*
Aquaporins (AQPs) are channel proteins that regulate the movement of water through the plasma membrane of secretory and… 
Highly Cited
1999
Highly Cited
1999
Tonicity-responsive enhancer binding protein, a rel-like protein that stimulates transcription in response to hypertonicity.
Hypertonicity (most often present as high salinity) is stressful to the cells of virtually all organisms. Cells survive in a… 
Highly Cited
1998
Highly Cited
1998
Cis- and trans-acting factors regulating transcription of the BGT1 gene in response to hypertonicity.
We have previously identified a tonicity-responsive enhancer (TonE) in the promoter region of the canine BGT1 gene. TonE mediates… 
Review
1995
Review
1995
Molecular basis of osmotic regulation.
  • M. Burg
  • American Journal of Physiology
  • 1995
  • Corpus ID: 19422459
Cells almost universally respond to the stress of long-term hyperosmolality by accumulating compatible organic osmolytes. This… 
Highly Cited
1994
Highly Cited
1994
Induction of gene expression by heat shock versus osmotic stress.
Elevated temperature rapidly increases expression of genes for heat shock proteins (HSP), including HSP-70. The response is… 
Highly Cited
1993
Highly Cited
1993
Medium tonicity regulates expression of the Na(+)- and Cl(-)-dependent betaine transporter in Madin-Darby canine kidney cells by increasing transcription of the transporter gene.
Betaine is one of the major compatible osmolytes accumulated by kidney derived Madin-Darby canine kidney cells cultured in… 
Highly Cited
1991
Highly Cited
1991
Taurine behaves as an osmolyte in Madin-Darby canine kidney cells. Protection by polarized, regulated transport of taurine.
Using a clonal growth assay, we demonstrated that taurine, a nonperturbing osmolyte accumulated in kidney medulla, brain, and… 
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