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hyperosmotic response
Known as:
HOG response
, hypertonic response
, response to hypertonicity
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene…
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Highly Cited
2008
Highly Cited
2008
Phospholipase Dα3 Is Involved in the Hyperosmotic Response in Arabidopsis
Yueyun Hong
,
Xiangqing Pan
,
R. Welti
,
Xuemin Wang
The Plant Cell Online
2008
Corpus ID: 9950892
Rapid activation of phospholipase D (PLD), which hydrolyzes membrane lipids to generate phosphatidic acid (PA), occurs under…
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Review
2004
Review
2004
MAP kinases and the adaptive response to hypertonicity: functional preservation from yeast to mammals.
D. Sheikh-Hamad
,
M. Gustin
AJP - Renal Physiology
2004
Corpus ID: 15172084
The adaptation to hypertonicity in mammalian cells is driven by multiple signaling pathways that include p38 kinase, Fyn, the…
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Review
2001
Review
2001
Physiological regulation of cyclooxygenase-2 in the kidney.
Raymond C. Harris
,
M. Breyer
AJP - Renal Physiology
2001
Corpus ID: 11560160
In adult mammalian kidney, cyclooxygenase-2 (COX-2) expression is found in a restricted subpopulation of cells. The two sites of…
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Highly Cited
2001
Highly Cited
2001
Salivary Acinar Cells from Aquaporin 5-deficient Mice Have Decreased Membrane Water Permeability and Altered Cell Volume Regulation*
Carissa M Krane
,
J. E. Melvin
,
+4 authors
A. Menon
Journal of Biological Chemistry
2001
Corpus ID: 23310916
Aquaporins (AQPs) are channel proteins that regulate the movement of water through the plasma membrane of secretory and…
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Highly Cited
1999
Highly Cited
1999
Tonicity-responsive enhancer binding protein, a rel-like protein that stimulates transcription in response to hypertonicity.
H. Miyakawa
,
S. K. Woo
,
S. Dahl
,
J. Handler
,
H. Kwon
Proceedings of the National Academy of Sciences…
1999
Corpus ID: 45805831
Hypertonicity (most often present as high salinity) is stressful to the cells of virtually all organisms. Cells survive in a…
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Highly Cited
1998
Highly Cited
1998
Cis- and trans-acting factors regulating transcription of the BGT1 gene in response to hypertonicity.
H. Miyakawa
,
S. K. Woo
,
Ching-Pu Chen
,
S. Dahl
,
J. Handler
,
H. Kwon
AJP - Renal Physiology
1998
Corpus ID: 4409642
We have previously identified a tonicity-responsive enhancer (TonE) in the promoter region of the canine BGT1 gene. TonE mediates…
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Review
1995
Review
1995
Molecular basis of osmotic regulation.
M. Burg
American Journal of Physiology
1995
Corpus ID: 19422459
Cells almost universally respond to the stress of long-term hyperosmolality by accumulating compatible organic osmolytes. This…
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Highly Cited
1994
Highly Cited
1994
Induction of gene expression by heat shock versus osmotic stress.
D. Sheikh-Hamad
,
A. García-Pérez
,
J. Ferraris
,
E. Peters
,
M. Burg
American Journal of Physiology
1994
Corpus ID: 24533328
Elevated temperature rapidly increases expression of genes for heat shock proteins (HSP), including HSP-70. The response is…
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Highly Cited
1993
Highly Cited
1993
Medium tonicity regulates expression of the Na(+)- and Cl(-)-dependent betaine transporter in Madin-Darby canine kidney cells by increasing transcription of the transporter gene.
Shinichi Uchida
,
A. Yamauchi
,
A. Preston
,
H. Kwon
,
J. Handler
Journal of Clinical Investigation
1993
Corpus ID: 682975
Betaine is one of the major compatible osmolytes accumulated by kidney derived Madin-Darby canine kidney cells cultured in…
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Highly Cited
1991
Highly Cited
1991
Taurine behaves as an osmolyte in Madin-Darby canine kidney cells. Protection by polarized, regulated transport of taurine.
S. Uchida
,
T. Nakanishi
,
H. Kwon
,
A. Preston
,
J. Handler
Journal of Clinical Investigation
1991
Corpus ID: 12680286
Using a clonal growth assay, we demonstrated that taurine, a nonperturbing osmolyte accumulated in kidney medulla, brain, and…
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