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hyperosmotic response

Known as: HOG response, hypertonic response, response to hypertonicity 
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene… 
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
Rapid activation of phospholipase D (PLD), which hydrolyzes membrane lipids to generate phosphatidic acid (PA), occurs under… 
Review
2006
Review
2006
Cellular responses induced by stress are essential for the survival of cells under adverse conditions. These responses, resulting… 
Review
2004
Review
2004
The adaptation to hypertonicity in mammalian cells is driven by multiple signaling pathways that include p38 kinase, Fyn, the… 
Review
2001
Review
2001
  • R. Harris, M. Breyer
  • American journal of physiology. Renal physiology
  • 2001
  • Corpus ID: 11560160
In adult mammalian kidney, cyclooxygenase-2 (COX-2) expression is found in a restricted subpopulation of cells. The two sites of… 
Highly Cited
2001
Highly Cited
2001
Aquaporins (AQPs) are channel proteins that regulate the movement of water through the plasma membrane of secretory and… 
Highly Cited
1999
Highly Cited
1999
Hypertonicity (most often present as high salinity) is stressful to the cells of virtually all organisms. Cells survive in a… 
Review
1995
Review
1995
  • M. Burg
  • The American journal of physiology
  • 1995
  • Corpus ID: 19422459
Cells almost universally respond to the stress of long-term hyperosmolality by accumulating compatible organic osmolytes. This… 
Highly Cited
1994
Highly Cited
1994
Elevated temperature rapidly increases expression of genes for heat shock proteins (HSP), including HSP-70. The response is… 
Highly Cited
1993
Highly Cited
1993
Betaine is one of the major compatible osmolytes accumulated by kidney derived Madin-Darby canine kidney cells cultured in… 
Highly Cited
1991
Highly Cited
1991
Using a clonal growth assay, we demonstrated that taurine, a nonperturbing osmolyte accumulated in kidney medulla, brain, and…