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hyperforin

Known as: 4-hydroxy-6-methyl-1,3,7-tris(3-methyl-2-butenyl)-5-(2-methyl-1-oxopropyl)-6-(4-methyl-3-pentenyl) bicyclo(3.3.1)non-3-ene-2,9-dione, Hiperforina, Hyperforine 
National Institutes of Health

Related topics

Related topics

7 relations

Narrower (2)

IDN5607IDN5706

Broader (2)

PhloroglucinolTerpenes
analogs & derivativesoctahydrohyperforintetrahydrohyperforin

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
The effect of St. John's wort on the pharmacokinetics, metabolism and biliary excretion of finasteride and its metabolites in healthy men.
2006
2006
Hyperforin inhibits MMP-9 secretion by B-CLL cells and microtubule formation by endothelial cells
We previously reported that hyperforin (HF), a natural phloroglucinol purified from Saint John's wort, can induce the apoptosis… 
Highly Cited
2005
Highly Cited
2005
Aristoforin, a Novel Stable Derivative of Hyperforin, Is a Potent Anticancer Agent
Hyperforin, a natural product of St. John's wort (Hypericum perforatum L.), has a number of pharmacological activities, including… 
2004
2004
Detection of hypericins in the "red glands" of Hypericum elodes by ESI-MS/MS.
2004
2004
In vitro metabolism of hyperforin in rat liver microsomal systems.
Hyperforin is an important active component of St. John's wort (Hypericum perforatum) that has been suggested to be responsible… 
2002
2002
Rapid quantification of constituents in St. John's wort extracts by NIR spectroscopy.
Highly Cited
2001
Highly Cited
2001
Adhyperforin as a contributor to the effect of Hypericum perforatum L. in biochemical models of antidepressant activity.
2001
2001
Catalytic inhibition of human DNA topoisomerase IIalpha by hypericin, a naphthodianthrone from St. John's wort (Hypericum perforatum).
Highly Cited
2001
Highly Cited
2001
In vitro binding studies with two hypericum perforatum extracts--hyperforin, hypericin and biapigenin--on 5-HT6, 5-HT7, GABA(A)/benzodiazepine, sigma, NPY-Y1/Y2 receptors and dopamine transporters.
Interactions between neurotransmitter receptors involved in the pathophysiology of depression, anxiety and ethanol consumption… 
Highly Cited
1992
Highly Cited
1992
Adhyperforin: A Homologue of Hyperforin from Hypericum perforatum
Ponglux. D., Wongseripipatana. S., Aim), N., Nishimura, M. IshikaWa. M., Sada, H., Haginiwa. J., Sakai, S. (1990) Chem. Pharm… 
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