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hydrodolasetron

National Institutes of Health

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IndolesQuinolizines

Papers overview

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2012
2012
Optimization of sample pretreatment methods for simultaneous determination of dolasetron and hydrodolasetron in human plasma by HPLC-ESI-MS.
A high-performance liquid chromatographic method coupled with electrospray mass spectrometry was developed for the simultaneous… 
2005
2005
Antiemetics of the 5-Hydroxytryptamine 3A Antagonist Class Inhibit Muscle Nicotinic Acetylcholine Receptors
Antagonists of the serotonergic 5-hydroxytryptamine 3A receptor (5-HT3AR) and muscle nicotinic acetylcholine receptors (nAChR… 
2005
2005
Lack of effect of aprepitant on the pharmacokinetics of hydrodolasetron in CYP2D6 extensive and poor metabolizers
Review
2000
Review
2000
A review of dolasetron as management of nausea and vomiting in cancer patients
Objective. To systematically review the literature about the pharmacology, pharmacokinetics, efficacy, dosing, and adverse… 
1999
1999
Pharmacokinetics of dolasetron with coadministration of cimetidine or rifampin in healthy subjects
Purpose: Dolasetron is a selective 5-HT3 receptor antagonist. The purpose of this study was to determine the effect of cimetidine… 
1999
1999
Pharmacokinetics of intravenous dolasetron in cancer patients receiving high-dose cisplatin-containing chemotherapy.
Dolasetron mesylate (MDL 73,147, Anzemet, Hoechst Marion Roussel, Kansas City, MO) is a 5-HT ( 3 ) receptor antagonist undergoing… 
1998
1998
Effect of Infusion Rate on the Pharmacokinetics and Tolerance of Intravenous Dolasetron Mesylate
OBJECTIVE To evaluate the safety, tolerance, and pharmacokinetics of dolasetron mesylate and its active metabolite… 
1997
1997
Pharmacokinetics of Dolasetron after Oral and Intravenous Administration of Dolasetron Mesylate in Healthy Volunteers and Patients with Hepatic Dysfunction
In previous studies, dolasetron was shown to have both renal and hepatic elimination mechanisms. This study was conducted to… 
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