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OBJECTIVE: To review the pharmacology, efficacy, and safety of efalizumab for the treatment of moderate to severe plaque… Expand The pharmacokinetics of hu1124, a human anti-CD11a antibody, were investigated in human subjects with psoriasis. CD11a is a… Expand BACKGROUND
Anti-CD11a (hu1124) is a humanized monoclonal antibody directed against the CD11a subunit of LFA-1. This study… Expand BIOLOGIC agents have been used in transplantation in the prophylaxis of rejection, in the induction phase of therapy, and in the… Expand BACKGROUND
CD11a/CD18 comprise subunits of leukocyte function associated antigen (LFA-1), a T-cell surface molecule important in… Expand Genentech and XOMA are collaborating in the development of a humanized monoclonal antibody, hu1124 (anti-CD11a), which has the… Expand