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homoserine dehydrogenase activity

Catalysis of the reaction: L-homoserine + NADP+ = L-aspartate-4-semialdehyde + NADPH + H+. [EC:1.1.1.3]
National Institutes of Health

Papers overview

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2006
2006
MICROBIAL PRODUCTION OF L-LYSINE PRODUCTION BY MUTANTS SENSITIVE THREONINE OR METHIONINE
  • 2006
  • Corpus ID: 133611836
Some prototrophic revertants from a homoserine auxotroph of Brevibacterium flavum No. 2247 (ATCC No. 14067), which grew as… 
2002
2002
Proteolysis of the Bifunctional Methionine-repressible Aspartokinase II-Homoserine Dehydrogenase II of Escherichia coli K 12
  • 2002
  • Corpus ID: 43587920
The dimeric bifunctional enzyme aspartokinase II-homoserine dehydrogenase II (M, = 2 x 88,000) of Escherichia coli K12 can be… 
1990
1990
[Development of the vector-host system in Corynebacterium. Cloning and expression of homoserine dehydrogenase and homoserine kinase genes in Corynebacterium cells].
Novel cloning vectors for glutamic acid producing bacteria have been constructed. The cryptic plasmid pBO1 (4.4 kb) from… 
1983
1983
A triglobular model for the polypeptide chain of aspartokinase I-homoserine dehydrogenase I of Escherichia coli.
Limited proteolysis of aspartokinase I-homoserine dehydrogenase I from Escherichia coli by type VI protease from Streptomyces… 
1980
1980
[Funtional study of gene relA in the expression of amino acid operons. III. The effect of the allelic state of gene relA on the derepression of the threonine and isoleucine-valine operons of…
During the derepression of threonine and isoleucine-valine operons the increase of activity of homoserine dehydrogenase and… 
1978
1978
Threonine inhibition of the aspartokinase--homoserine dehydrogenase I of Escherichia coli. Stopped-flow kinetics and the cooperativity of inhibition of the homoserine dehydrogenase activity.
1976
1976
Thialysine-resistant mutant of Salmonella typhimurium with a lesion in the thrA gene.
A mutant of Salmonella typhimurium was selected for its spontaneous resistance to the lysine analog, thialysine (S-2-aminoethyl… 
1975
1975
The threonine-sensitive homoserine dehydrogenase and aspartokinase activities of Escherichia coli K12. Distribution and accessibility to antibodies of some epitopes of the bifunctional enzyme.
In the presence of l-threonine, the allosteric effector, most of the antigenic determinants situated in the aspartokinase region… 
1975
1975
The threonine-sensitive homoserine dehydrogenase and aspartokinase activities of Escherichia coli K12. Specific inactivation of the homoserine dehydrogenase activity by the affinity label, 2-amino-4…
2-Amino-4-oxo-5-chloropentanoic acid inactivates specifically the homoserine dehydrogenase activity of the bifunctional enzyme… 
Highly Cited
1968
Highly Cited
1968
The threonine-sensitive homoserine dehydrogenase and aspartokinase activities of Escherichia coli K 12. 4. Isolation, molecular weight, amino acid analysis and behaviour of the sulfhydryl groups of…
The interactions between the catalytic regions of the subunit of the bifunctional enzyme aspartokinase I-homoserine dehydrogenase…