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higenamine

Known as: 1-(p-hydroxybenzyl)-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline, O-demethylcoclaurine, norcoclaurine 
National Institutes of Health

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7 relations

Broader (6)

Adrenergic beta-AgonistsAlkaloidsAnti-Inflammatory Agents, Non-SteroidalCardiotonic Agents

Narrower (1)

higenamine hydrochloride, (S)-isomer

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
A pharmacokinetics study of orally administered higenamine in rats using LC-MS/MS for doping control analysis.
According to WADA guidelines, the presence of Higenamine (HG) in urine should not be ≥ 10 ng/mL. HG is widely found in materials… 
2007
2007
High-yield expression and purification of isotopically labeled norcoclaurine synthase, a Bet v 1-homologous enzyme, from Thalictrum flavum for NMR studies.
2007
2007
Tolerability of higenamine hydrochloride in healthy volunteers
Objective To investigate the tolerability of higenamine hydrochloride(HG)in healthy volunteers.Methods Thirty-two volunteers were… 
2006
2006
Enantiomers of higenamine inhibit LPS-induced iNOS in a macrophage cell line and improve the survival of mice with experimental endotoxemia.
2004
2004
Determination of higenamine in plasma by HPLC-ECD and study on its pharmacokinetics
OBJECTIVE To establish a HPLC-ECD assay for the determination of higenamine in plasma and to study its pharmacokinet-ics.METHODS… 
2002
2002
The effects of higenamine on LPS-induced experimental disseminated intravascular coagulation (DIC) in rats.
The effect of higenamine, a benzyl-tetrahydroisoquinoline alkaloid of the roots of Aconitum spp. (Ranunculaceae), on disseminated… 
1999
1999
Inhibitory effects of higenamine on dopamine content in PC12 cells.
The inhibitory effects of (+/-)-higenamine, a benzylisoquinoline alkaloid, on dopamine biosynthesis in PC12 cells were… 
1999
1999
Benzylisoquinoline alkaloids from gnetum parvifolium
The investigation of the chemical constituents from the lianas of Gnetum parvifolium resulted in the isolation of three new… 
1998
1998
Comparison of Inodilator Effect of Higenamine, YS49, YS51, Tetrahydroisoquinoline Analogs, and Dobutamine in the Rat
Tetrahydroisoquinoline (THI) alkaloids can be considered as cyclized derivatives of simple phenylethylamines. Many of them… 
1996
1996
Potentiation by higenamine of the aconitine-induced positive chronotropic effect in isolated right atria of mice: the effects of cholera toxin, forskolin and pertussis toxin.
Aconitine and higenamine are the major cardioactive compounds obtained from processed aconite. The chronotropic interaction… 
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