heptaplatin

 
National Institutes of Health

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SKI 2053R

Papers overview

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2016
2016
Cheminformatics and System Chemistry of Cisplatin, Carboplatin, Nedaplatin,Oxaliplatin, Heptaplatin and Lobaplatin as Anti-Cancer Nano Drugs: ACombined Computational and Experimental Study
The anti-cancer Nano drugs Cisplatin, Carboplatin, Nedaplatin, Oxaliplatin, Heptaplatin and Lobaplatin were characterized by… (More)
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2014
2014
Chemosensitivity of resistant colon cancer cell lines to lobaplatin, heptaplatin, and dicycloplatin.
PURPOSE Lobaplatin, heptaplatin, and dicycloplatin are three new platinum drugs. The aim of this study is to investigate the… (More)
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2011
2011
A novel water-soluble heptaplatin analogue with improved antitumor activity and reduced toxicity.
A novel water-soluble heptaplatin analogue, cis-[(4R,5R)-4,5-bis-(aminomethyl)-2-isopropyl-1,3-dioxolane](3-hydroxy-1,1… (More)
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Highly Cited
2010
Highly Cited
2010
The status of platinum anticancer drugs in the clinic and in clinical trials.
Since its approval in 1979 cisplatin has become an important component in chemotherapy regimes for the treatment of ovarian… (More)
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2010
2010
Embryo-feto-toxicity of anticancer drug, heptaplatin in laboratory mice.
The present study was conducted to test the possible teratogenic and toxic effects of anti-cancer drug heptaplatin (SKI 2053) on… (More)
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2009
2009
Randomized, multicenter, phase III trial of heptaplatin 1-hour infusion and 5-fluorouracil combination chemotherapy comparing with cisplatin and 5-fluorouracil combination chemotherapy in patients…
PURPOSE Heptaplatin (Sunpla) is a cisplatin derivative. A phase IIb trial using heptaplatin resulted in a 34% response rate with… (More)
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2006
2006
Anti-tumor activity of heptaplatin in combination with 5-fluorouracil or paclitaxel against human head and neck cancer cells in vitro.
Heptaplatin (HTP), a newly developed platinum analog, has been approved for the treatment of gastric cancers in South Korea. In… (More)
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2004
2004
Molecular mechanisms of heptaplatin effective against cisplatin-resistant cancer cell lines: less involvement of metallothionein
Heptaplatin is a new platinum derivative with anticancer activity against various cancer cell lines, including cisplatin… (More)
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2004
2004
Combination Chemotherapy with 5-Fluorouracil and Heptaplatin as First-line Treatment in Patients with Advanced Gastric Cancer
Heptaplatin is a recently developed platinum derivative. This agent has been reported to have a response rate of 17% as a single… (More)
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2002
2002
Nephrotoxicity of heptaplatin: a randomized comparison with cisplatin in advanced gastric cancer
Abstract Purpose. Heptaplatin is a newly developed platinum derivative which has been reported to be less toxic than cisplatin… (More)
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