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heptaplatin

 
National Institutes of Health

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SKI 2053R

Papers overview

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Highly Cited
2016
Highly Cited
2016
Study of the Role of Anti-Cancer Molecules with Different Sizes for Decreasing Corresponding Bulk Tumor Multiple Organs or Tissues
The intermolecular forces between anti–cancer molecules such as Cisplatin, Carboplatin, Oxaliplatin, Nedaplatin, Lobaplation… Expand
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2014
2014
Synthesis, anticancer activity and toxicity of a water-soluble 4S,5S-derivative of heptaplatin, cis-{Pt(II)[(4S,5S)-4,5-bis(aminomethyl)-2-isopropyl-1,3-dioxolane]·(3-hydroxyl-cyclobutane-1,1…
A water-soluble 4S,5S-derivative of heptaplatin, cis-{Pt(II)[(4S,5S)-4,5-bis(aminomethyl)-2-isopropyl-1,3-dioxolane]·(3-hydroxyl… Expand
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2011
2011
A novel water-soluble heptaplatin analogue with improved antitumor activity and reduced toxicity.
A novel water-soluble heptaplatin analogue, cis-[(4R,5R)-4,5-bis-(aminomethyl)-2-isopropyl-1,3-dioxolane](3-hydroxy-1,1… Expand
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Highly Cited
2010
Highly Cited
2010
The status of platinum anticancer drugs in the clinic and in clinical trials.
Since its approval in 1979 cisplatin has become an important component in chemotherapy regimes for the treatment of ovarian… Expand
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2009
2009
Randomized, multicenter, phase III trial of heptaplatin 1-hour infusion and 5-fluorouracil combination chemotherapy comparing with cisplatin and 5-fluorouracil combination chemotherapy in patients…
  • K. Lee, M. Hyun, +14 authors S. Lee
  • Cancer research and treatment : official journal…
  • 2009
    • Corpus ID: 26703423
PURPOSE Heptaplatin (Sunpla) is a cisplatin derivative. A phase IIb trial using heptaplatin resulted in a 34% response rate with… Expand
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2006
2006
Anti-tumor activity of heptaplatin in combination with 5-fluorouracil or paclitaxel against human head and neck cancer cells in vitro
Heptaplatin (HTP), a newly developed platinum analog, has been approved for the treatment of gastric cancers in South Korea. In… Expand
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2004
2004
Molecular mechanisms of heptaplatin effective against cisplatin-resistant cancer cell lines: less involvement of metallothionein
BackgroundHeptaplatin is a new platinum derivative with anticancer activity against various cancer cell lines, including… Expand
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2004
2004
Combination Chemotherapy with 5-Fluorouracil and Heptaplatin as First-line Treatment in Patients with Advanced Gastric Cancer
Heptaplatin is a recently developed platinum derivative. This agent has been reported to have a response rate of 17% as a single… Expand
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2003
2003
Pilot Study of Heptaplatin, UFT-E and Leucovorin in Advanced Gastric Carcinoma.
  • S. Oh, S. Yoon, +8 authors J. Kim
  • Cancer research and treatment : official journal…
  • 2003
    • Corpus ID: 22364455
PURPOSE Heptaplatin (SKI-2053R, Sunpla ), a new platinum analogue which has a better toxicity profile than cisplatin, has been… Expand
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2002
2002
Nephrotoxicity of heptaplatin: a randomized comparison with cisplatin in advanced gastric cancer
HeadingAbstractPurpose. Heptaplatin is a newly developed platinum derivative which has been reported to be less toxic than… Expand
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