heparin

Known as: Eparina, heparin unfractionated, Heparinate 
A highly acidic mucopolysaccharide formed of equal parts of sulfated D-glucosamine and D-glucuronic acid with sulfaminic bridges. The molecular… (More)

Topic mentions per year

Topic mentions per year

1935-2018
01000200019352017

Papers overview

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Highly Cited
2003
Highly Cited
2003
BACKGROUND Patients with cancer have a substantial risk of recurrent thrombosis despite the use of oral anticoagulant therapy. We… (More)
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Highly Cited
2003
Highly Cited
2003
CONTEXT The direct thrombin inhibitor bivalirudin has been associated with better efficacy and less bleeding than heparin during… (More)
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Highly Cited
2002
Highly Cited
2002
Branching morphogenesis in the mammalian lung and Drosophila trachea relies on the precise localization of secreted modulators of… (More)
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Highly Cited
2001
Highly Cited
2001
BACKGROUND Heparin-induced thrombocytopenia is a relatively common antibody-mediated drug reaction. We studied the temporal… (More)
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Highly Cited
2000
Highly Cited
2000
The crystal structure of a dimeric 2:2:2 FGF:FGFR:heparin ternary complex at 3 A resolution has been determined. Within each 1:1… (More)
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Highly Cited
1997
Highly Cited
1997
  • The New England journal of medicine
  • 1997
BACKGROUND Blockade of the platelet glycoprotein IIb/IIIa receptor with abciximab (a monoclonal-antibody Fab fragment directed… (More)
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Highly Cited
1995
Highly Cited
1995
BACKGROUND Heparin-induced thrombocytopenia, defined by the presence of heparin-dependent IgG antibodies, typically occurs five… (More)
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Highly Cited
1992
Highly Cited
1992
BACKGROUND Blood vessel growth is necessary for normal tissue homeostatis and contributes to solid tumor growth. Methods to… (More)
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Highly Cited
1991
Highly Cited
1991
The role of low affinity, heparin-like binding sites for basic fibroblast growth factor (bFGF) was investigated in CHO cells… (More)
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Highly Cited
1989
Highly Cited
1989
A growth factor for vascular endothelial cells was identified in the media conditioned by bovine pituitary follicular cells and… (More)
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