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heparin-binding EGF-like growth factor

Known as: Heparin-binding EGF-like Growth-Factor, Heparin binding EGF like Growth Factor, HB-EGF 
An EGF family member that is expressed in a variety of hematopoietic, endothelial, vascular smooth muscle, and epithelial cells. It is synthesized as… 
National Institutes of Health

Related topics

Related topics

12 relations
HBEGF geneHBEGF wt AlleleIn BloodProcess of secretion

Narrower (3)

HBEGF protein, humanShort Form HB-EGFdiphtheria toxin receptor

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2007
2007
Juxtacrine Activation of EGFR by Membrane-anchored HB-EGF Protects Epithelial Cells from Anoikis While Maintaining an Epithelial Phenotype
Juxtacrine Activation of EGFR by Membrane-anchored HB-EGF Protects Epithelial Cells from Anoikis While Maintaining an Epithelial… 
2004
2004
Target for Ovarian Cancer Therapy Heparin-Binding EGF-Like Growth Factor Is a Promising
Ovarian cancer is the most frequent cause of cancer death among all gynecologic cancers. We demonstrate here that… 
Review
2003
Review
2003
[Membrane-anchored heparin-binding EGF-like growth factor processing by ADAM12 in cardiac hypertrophy].
G-protein coupled receptor(GPCR) agonists are well-known inducers of cardiac hypertrophy. We found that the shedding of HB-EGF… 
2000
2000
A nontoxic diphtheria toxin analogue inhibits neonatal bladder smooth muscle cell proliferation.
Highly Cited
1999
Highly Cited
1999
Contact-dependent Growth Inhibition and Apoptosis of Epidermal Growth Factor (EGF) Receptor-expressing Cells by the Membrane-anchored Form of Heparin-binding EGF-like Growth Factor*
Heparin-binding epidermal growth factor-like growth factor (HB-EGF) transduces mitogenic signals through the EGF receptor (EGFR… 
1997
1997
Renal epidermal growth factor precursor: proteolytic processing in an in vitro cell-free system.
1996
1996
Regulation of heparin-binding EGF-like growth factor expression by phorbol ester in a human hepatoma-derived cell line.
1994
1994
Modification of immunoreactive EGF and EGF receptor after acute tubular necrosis induced by tobramycin or cisplatin.
Acute tubular necrosis induced by aminoglycoside antibiotics and various other nephrotoxins is followed by a regenerative process… 
1991
1991
Actin-binding proteins involved in the capping of epidermal growth factor receptors in A431 cells.
1988
1988
Contraction of guinea pig trachea by epidermal growth factor--urogastrone.
To evaluate further the action of epidermal growth factor - urogastrone (EGF-URO) in smooth muscle systems, we examined the… 
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