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HBEGF gene

Known as: DTR, DIPHTHERIA TOXIN RECEPTOR, HEPARIN-BINDING EGF 
This gene plays a role in macrophage-mediated cellular proliferation and growth regulation in fibroblasts and smooth muscle cells.
National Institutes of Health

Related topics

Related topics

11 relations
Cell Proliferation Regulatory ProcessDiphtheriaHBEGF protein, humanHomo sapiens

Broader (1)

Genes

Narrower (1)

HBEGF wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Maternal biomarkers for fetal heart failure in fetuses with congenital heart defects or arrhythmias
2015
2015
Depletion of alveolar macrophages in CD11c diphtheria toxin receptor mice produces an inflammatory response
Alveolar macrophages play a critical role in initiating the immune response to inhaled pathogens and have been shown to be the… 
2013
2013
Adjuvant effect of diphtheria toxin after mucosal administration in both wild type and diphtheria toxin receptor engineered mouse strains.
2008
2008
Thrombin mediates mitogenesis and survival of human endothelial cells through distinct mechanisms.
Thrombin has been reported to play a pivotal role in the initiation of angiogenesis by indirectly regulating and organizing a… 
2006
2006
Canonical WNT signaling pathway and human AREG.
AREG (Amphiregulin), BTC (beta-cellulin), EGF, EPGN (Epigen), EREG (Epiregulin), HBEGF, NRG1, NRG2, NRG3, NRG4 and TGFA (TGFalpha… 
2002
2002
Dual source and target of heparin-binding EGF-like growth factor during the onset of implantation in the hamster.
Heparin binding EGF-like growth factor (HB-EGF), encoded by the Hegfl gene, is considered as an important mediator of embryo… 
1999
1999
Granulocyte-macrophage colony-stimulating factor induces expression of heparin-binding epidermal growth factor-like growth factor/diphtheria toxin receptor and sensitivity to diphtheria toxin in…
Heparin-binding epidermal growth factor-like growth factor (HB-EGF) is a widely expressed EGF superfamily member that induces… 
1997
1997
High concentration of glucose increases mitogenic responsiveness to heparin-binding epidermal growth factor-like growth factor in rat vascular smooth muscle cells.
The effect of a high extracellular glucose concentration on the mitogenic response of rat vascular smooth muscle cells (SMCs) to… 
1995
1995
Mouse chromosomal location of three EGF receptor ligands: amphiregulin (Areg), betacellulin (Btc), and heparin-binding EGF (Hegfl).
The products of five distinct loci, Egf, Tgfa, Areg, Btc, and Hegfl act as ligands for the epidermal growth factor receptor. Egf… 
1995
1995
Increased mitogenic response to heparin-binding epidermal growth factor-like growth factor in vascular smooth muscle cells of diabetic rats.
We investigated the mitogenic effects of heparin-binding epidermal growth factor-like growth factor (HB-EGF) in vascular smooth… 
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