FAQ

hematopoietic stem cell homeostasis

Any biological process involved in the maintenance of the steady-state number of hematopoietic stem cells within a population of cells. [GOC:dph… (More)

Topic mentions per year

Topic mentions per year

1995-2018
02419952018

Papers overview

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2016
2016
BAF180 regulates cellular senescence and hematopoietic stem cell homeostasis through p21
BAF180 (also called PBRM1), a subunit of the SWI/SNF complex, plays critical roles in the regulation of chromatin remodeling and… (More)
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2015
2015
Cohesin loss alters adult hematopoietic stem cell homeostasis, leading to myeloproliferative neoplasms
The cohesin complex (consisting of Rad21, Smc1a, Smc3, and Stag2 proteins) is critically important for proper sister chromatid… (More)
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2015
2015
IP3 3-kinase B controls hematopoietic stem cell homeostasis and prevents lethal hematopoietic failure in mice.
Tight regulation of hematopoietic stem cell (HSC) homeostasis ensures lifelong hematopoiesis and prevents blood cancers. The… (More)
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2015
2015
SHIP1-expressing mesenchymal stem cells regulate hematopoietic stem cell homeostasis and lineage commitment during aging.
Hematopoietic stem cell (HSC) self-renewal and lineage choice are subject to intrinsic control. However, this intrinsic… (More)
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2012
2012
TET2 is essential for survival and hematopoietic stem cell homeostasis
Ten-Eleven-Translocation 2 (TET2) is an enzyme that catalyzes the conversion of 5-methylcytosine into 5-hydroxymethylcytosine (5… (More)
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2010
2010
Early B cell factor 2 regulates hematopoietic stem cell homeostasis in a cell-nonautonomous manner.
Hematopoiesis requires the interaction of hematopoietic stem cells (HSCs) with various stromal microenvironments. Here, we… (More)
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2009
2009
Pivotal role for glycogen synthase kinase-3 in hematopoietic stem cell homeostasis in mice.
Hematopoietic stem cell (HSC) homeostasis depends on the balance between self renewal and lineage commitment, but what regulates… (More)
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2008
2008
Fine-tuning of hematopoietic stem cell homeostasis: novel role for ubiquitin ligase.
Homeostasis of hematopoietic stem cells (HSCs) is a tightly regulated process, controlled by intrinsic and extrinsic signals… (More)
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2004
2004
Disruption of PLZP in mice leads to increased T-lymphocyte proliferation, cytokine production, and altered hematopoietic stem cell homeostasis.
Deregulated function of members of the POK (POZ and Kruppel) family of transcriptional repressors, such as promyelocytic leukemia… (More)
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Highly Cited
2003
Highly Cited
2003
In vitro generation of long-term repopulating hematopoietic stem cells by fibroblast growth factor-1.
The role of fibroblast growth factors and their receptors (FGFRs) in the regulation of normal hematopoietic stem cells is unknown… (More)
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