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hematopoietic stem cell homeostasis

Any biological process involved in the maintenance of the steady-state number of hematopoietic stem cells within a population of cells. [GOC:dph… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
miR-146a–Traf6 regulatory axis controls autoimmunity and myelopoiesis, but is dispensable for hematopoietic stem cell homeostasis and tumor suppression
Significance Aberrant inflammation is the root cause of numerous human diseases, from autoimmunity to cancer. microRNA-146a (miR… Expand
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2016
2016
BAF180 regulates cellular senescence and hematopoietic stem cell homeostasis through p21
BAF180 (also called PBRM1), a subunit of the SWI/SNF complex, plays critical roles in the regulation of chromatin remodeling and… Expand
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Highly Cited
2015
Highly Cited
2015
Cohesin loss alters adult hematopoietic stem cell homeostasis, leading to myeloproliferative neoplasms
Mullenders et al. report that loss of cohesin alters stem cell homeostasis and myelopoiesis, facilitating the development of a… Expand
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Highly Cited
2015
Highly Cited
2015
Mitochondrial metabolism in hematopoietic stem cells requires functional FOXO3.
Hematopoietic stem cells (HSC) are primarily dormant but have the potential to become highly active on demand to reconstitute… Expand
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Highly Cited
2012
Highly Cited
2012
TET2 is essential for survival and hematopoietic stem cell homeostasis
Ten-Eleven-Translocation 2 (TET2) is an enzyme that catalyzes the conversion of 5-methylcytosine into 5-hydroxymethylcytosine (5… Expand
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Highly Cited
2011
Highly Cited
2011
Conserved Regulation of p53 Network Dosage by MicroRNA–125b Occurs through Evolving miRNA–Target Gene Pairs
MicroRNAs regulate networks of genes to orchestrate cellular functions. MiR-125b, the vertebrate homologue of the Caenorhabditis… Expand
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2010
2010
Early B cell factor 2 regulates hematopoietic stem cell homeostasis in a cell-nonautonomous manner.
Hematopoiesis requires the interaction of hematopoietic stem cells (HSCs) with various stromal microenvironments. Here, we… Expand
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Highly Cited
2009
Highly Cited
2009
Pivotal role for glycogen synthase kinase-3 in hematopoietic stem cell homeostasis in mice.
Hematopoietic stem cell (HSC) homeostasis depends on the balance between self renewal and lineage commitment, but what regulates… Expand
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2004
2004
Disruption of PLZP in Mice Leads to Increased T-Lymphocyte Proliferation, Cytokine Production, and Altered Hematopoietic Stem Cell Homeostasis
ABSTRACT Deregulated function of members of the POK (POZ and Krüppel) family of transcriptional repressors, such as… Expand
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Highly Cited
2003
Highly Cited
2003
In vitro generation of long-term repopulating hematopoietic stem cells by fibroblast growth factor-1.
The role of fibroblast growth factors and their receptors (FGFRs) in the regulation of normal hematopoietic stem cells is unknown… Expand
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