FAQ

hellebrin

Known as: 3,5,14-Trihydroxy-19-oxobufa-20,22-dienolide, corelborin, corelborine 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1952-2017
01219522016

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
Hellebrin and its aglycone form hellebrigenin display similar in vitro growth inhibitory effects in cancer cells and binding profiles to the alpha subunits of the Na+/K+-ATPase
Surface-expressed Na+/K+-ATPase (NaK) has been suggested to function as a non-canonical cardiotonic steroid-binding receptor that… (More)
  • figure 1
  • table 1
  • figure 2
  • table 2
  • figure 3
Is this relevant?
2012
2012
Cytotoxic activity of some glycoconjugates including saponins and anthracyclines.
Many different glycoconjugates, including saponins (e.g., hellebrin) and anthracyclines (e.g., doxorubicin), are known to display… (More)
  • figure 1
  • table 1
  • figure 2
  • table 2
Is this relevant?
2010
2010
FTIR spectral signature of the effect of cardiotonic steroids with antitumoral properties on a prostate cancer cell line.
We show in the present work that the infrared (IR) spectrum of human PC-3 prostate cancer cells exposed to anticancer drugs could… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2008
2008
Anti-cancer natural product library from traditional chinese medicine.
The cure rates in cancer chemotherapy are affected by the development of drug resistance and severe side effects. Due to these… (More)
Is this relevant?
2003
2003
Apoptosis-mediated selective killing of malignant cells by cardiac steroids: maintenance of cytotoxicity and loss of cardiac activity of chemically modified derivatives.
Cardiac glycosides are commonly used drugs in clinical medicine. We analyzed the cytotoxic effect of six steroids belonging to… (More)
Is this relevant?
1987
1987
[Effect of cardiac glycosides on the calcium ion binding by biomembrane lipids].
By using methods of fluorescent and spine (electron paramagnetic resonance) probes it was shown that cardiac glycosides (digoxin… (More)
Is this relevant?
1974
1974
[Spectrophotometric determination of corelborin].
 
Is this relevant?
1973
1973
[Quantitative determination of corelborin in tablets using a spectrophotometric method].
 
Is this relevant?
1968
1968
[The effect of strophanthin, corelborin and cymarin on the cardiovascular system in patients with circulatory insufficiency following heart surgery].
 
Is this relevant?
1952
1952
[Clinical findings on the effect of Helleborus glycosides (corelborine) in circulatory insufficiency].
 
Is this relevant?