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hellebrin
Known as:
3,5,14-Trihydroxy-19-oxobufa-20,22-dienolide
, corelborin
, corelborine
National Institutes of Health
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Related topics
Related topics
1 relation
Broader (1)
Bufanolides
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Antiseizure potential of the ancient Greek medicinal plant Helleborus odorus subsp. cyclophyllus and identification of its main active principles.
T. Brillatz
,
M. Jacmin
,
+10 authors
J. Wolfender
Journal of ethnopharmacology
2020
Corpus ID: 218864030
2013
2013
Structure-activity relationship analysis of bufadienolide-induced in vitro growth inhibitory effects on mouse and human cancer cells.
Laetitia Moreno Y Banuls
,
E. Urban
,
+4 authors
M. Zehl
Journal of natural products
2013
Corpus ID: 35589637
The in vitro growth inhibitory effects of 27 bufadienolides and eight degradation products, with two cardenolides (ouabain and…
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2012
2012
Hellebrin and its aglycone form hellebrigenin display similar in vitro growth inhibitory effects in cancer cells and binding profiles to the alpha subunits of the Na+/K+-ATPase
Laetitia Moreno Y Banuls
,
A. Katz
,
+11 authors
R. Kiss
Molecular Cancer
2012
Corpus ID: 9968192
BackgroundSurface-expressed Na+/K+-ATPase (NaK) has been suggested to function as a non-canonical cardiotonic steroid-binding…
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2012
2012
Cytotoxic activity of some glycoconjugates including saponins and anthracyclines.
F. Ekholm
,
Á. Berényi
,
+5 authors
R. Leino
Carbohydrate research
2012
Corpus ID: 206470905
2011
2011
An approach to the synthesis and attachment of scillabiose to steroids
F. Ekholm
,
G. Schneider
,
J. Wölfling
,
R. Leino
Steroids
2011
Corpus ID: 43533900
2010
2010
FTIR spectral signature of the effect of cardiotonic steroids with antitumoral properties on a prostate cancer cell line.
Régis Gasper
,
T. Mijatovic
,
A. Bénard
,
Allison Derenne
,
R. Kiss
,
E. Goormaghtigh
Biochimica et biophysica acta
2010
Corpus ID: 27649499
2010
2010
Rapid structural identification of cytotoxic bufadienolide sulfates in toad venom from Bufo melanosticus by LC-DAD-MS(n) and LC-SPE-NMR.
Huimin Gao
,
M. Zehl
,
+5 authors
B. Kopp
Journal of natural products
2010
Corpus ID: 25756499
Toad venom, namely, "Chansu" in China, has been widely used for the treatment of heart failure, sores, pains, and various cancers…
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2008
2008
Anti-cancer natural product library from traditional chinese medicine.
V. B. Konkimalla
,
T. Efferth
Combinatorial chemistry & high throughput…
2008
Corpus ID: 26094247
The cure rates in cancer chemotherapy are affected by the development of drug resistance and severe side effects. Due to these…
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Highly Cited
2003
Highly Cited
2003
Apoptosis-mediated selective killing of malignant cells by cardiac steroids: maintenance of cytotoxicity and loss of cardiac activity of chemically modified derivatives.
D. Daniel
,
C. Süsal
,
B. Kopp
,
G. Opelz
,
P. Terness
International immunopharmacology
2003
Corpus ID: 34891121
1975
1975
Variant HeLa cells selected for their resistance to ouabain
H. M. Rosenberg
Journal of cellular physiology
1975
Corpus ID: 9291010
The cardiac glycoside, ouabain, normally kills HeLa cells at concentrations of about 10−7 m or greater. By treating a population…
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