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hellebrin

Known as: 3,5,14-Trihydroxy-19-oxobufa-20,22-dienolide, corelborin, corelborine 
 
National Institutes of Health

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Bufanolides

Papers overview

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2013
2013
Structure-activity relationship analysis of bufadienolide-induced in vitro growth inhibitory effects on mouse and human cancer cells.
The in vitro growth inhibitory effects of 27 bufadienolides and eight degradation products, with two cardenolides (ouabain and… Expand
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2012
2012
Hellebrin and its aglycone form hellebrigenin display similar in vitro growth inhibitory effects in cancer cells and binding profiles to the alpha subunits of the Na+/K+-ATPase
BackgroundSurface-expressed Na+/K+-ATPase (NaK) has been suggested to function as a non-canonical cardiotonic steroid-binding… Expand
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2010
2010
FTIR spectral signature of the effect of cardiotonic steroids with antitumoral properties on a prostate cancer cell line.
We show in the present work that the infrared (IR) spectrum of human PC-3 prostate cancer cells exposed to anticancer drugs could… Expand
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2010
2010
Rapid structural identification of cytotoxic bufadienolide sulfates in toad venom from Bufo melanosticus by LC-DAD-MS(n) and LC-SPE-NMR.
Toad venom, namely, "Chansu" in China, has been widely used for the treatment of heart failure, sores, pains, and various cancers… Expand
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2008
2008
Anti-cancer natural product library from traditional chinese medicine.
The cure rates in cancer chemotherapy are affected by the development of drug resistance and severe side effects. Due to these… Expand
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2003
2003
Apoptosis-mediated selective killing of malignant cells by cardiac steroids: maintenance of cytotoxicity and loss of cardiac activity of chemically modified derivatives.
Cardiac glycosides are commonly used drugs in clinical medicine. We analyzed the cytotoxic effect of six steroids belonging to… Expand
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1969
1969
The effect of strophanthin and Corelborin II on the gaseous composition of the blood in chronic circulatory insufficiency
 
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1968
1968
[The effect of strophanthin, corelborin and cymarin on the cardiovascular system in patients with circulatory insufficiency following heart surgery].
 
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1967
1967
[Effect of corelborine P, cymarin and strophanthin K on cardiovascular system of dogs with symptoms of cardiac insufficiency].
  • Saul Kit
  • Farmakologiia i toksikologiia
  • 1967
    • Corpus ID: 7157668
 
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1964
1964
[COMPARATIVE BIOLOGICAL EFFECTS OF STROPHANTHIN-K, CORELBORIN-P, CYMARIN AND PERIPLOCIN ON THE CAT HEART IN LESIONS INDUCED WITH ZINC HYDROXIDE].
  • Saul Kit
  • Farmakologiia i toksikologiia
  • 1964
    • Corpus ID: 2060745
 
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