FAQ

haptoglobin binding

Interacting selectively and non-covalently with a haptoglobin, any alpha2 globulin of blood plasma that can combine with free oxyhemoglobin to form a… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1958-2017
01219582017

Papers overview

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2008
2008
Rate of nitric oxide scavenging by hemoglobin bound to haptoglobin.
Cell-free hemoglobin, released from the red cell, may play a major role in regulating the bioavailability of nitric oxide. The… (More)
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2008
2008
Relevance of the amino acid conversions L144R (Zaragoza) and L159P (Zavalla) in the apolipoprotein A-I binding site for haptoglobin.
The high-density lipoprotein apolipoprotein A-I (ApoA-I) stimulates the enzyme lecithin-cholesterol acyltransferase (LCAT) in the… (More)
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2006
2006
Complex role of hemoglobin and hemoglobin-haptoglobin binding proteins in Haemophilus influenzae virulence in the infant rat model of invasive infection.
Haemophilus influenzae requires an exogenous heme source for aerobic growth in vitro. Hemoglobin or hemoglobin-haptoglobin… (More)
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2006
2006
Differential utilization by Haemophilus influenzae of haemoglobin complexed to the three human haptoglobin phenotypes.
Haemophilus influenzae has an absolute requirement for heme, which may be supplied as the haemoglobin-haptoglobin complex… (More)
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2004
2004
Reduced severity of middle ear infection caused by nontypeable Haemophilus influenzae lacking the hemoglobin/hemoglobin-haptoglobin binding proteins (Hgp) in a chinchilla model of otitis media.
Since Haemophilus influenzae lacks enzymes necessary for synthesis of the porphyrin ring, it has an absolute growth requirement… (More)
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2000
2000
Detection of phase variation in expression of proteins involved in hemoglobin and hemoglobin-haptoglobin binding by nontypeable Haemophilus influenzae.
Haemophilus influenzae can utilize different protein-bound forms of heme for growth in vitro. A previous study (I. Maciver, J. L… (More)
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1999
1999
Characterization of hgpA, a gene encoding a haemoglobin/haemoglobin-haptoglobin-binding protein of Haemophilus influenzae.
Haemophilus haemoglobin-haptoglobin complex and utilizes either as a sole source of haem. Previously, a DNA fragment was cloned… (More)
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1999
1999
Role of CCAA nucleotide repeats in regulation of hemoglobin and hemoglobin-haptoglobin binding protein genes of Haemophilus influenzae.
Haemophilus influenzae utilizes hemoglobin and hemoglobin-haptoglobin as heme sources. The H. influenzae hemoglobin- and… (More)
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1990
1990
Hemoglobin binding with haptoglobin: delineation of the haptoglobin binding site on the alpha-chain of human hemoglobin.
Previous studies from this laboratory employing a comprehensive synthetic overlapping peptide strategy showed that the alpha… (More)
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1976
1976
Kinetics of deoxyhemoglobin subunit dissociation determined by haptoglobin binding: estimation of the equilibrium constant from forward and reverse rates.
Deoxyhemoglobin tetramers dissociate into dimers very slowly, with half-times on the order of several hours. It is demonstrated… (More)
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