Semantic Scholar uses AI to extract papers important to this topic.
A facile total synthesis of hainanensine (1), a structurally unique Cephalotaxus alkaloid, via an effective acid-mediated… Expand The metabolism of HH07A in the rat has been investigated by GC-MS. After oral administration of HH07A, the rat urine was passed… Expand The metabolism of hainanensine derivative HH07A has been studied in vitro with rat microsomes. A method of HPLC-DAD was developed… Expand The effect of HH07A on DNA polymerase I in a cell free system was studied. The results showed that HH07A strongly inhibited the… Expand The effect of HH07A on the
growth of tumor cells in vitro was jnvestigated usingthe techniques
of cell growth… Expand The L1210 cell rapidly ceased to
proliferate and its mitotic index decreased markedly after being
exposed to… Expand The effect of HH07A on the growth of tumor cells in vitro was investigated using the techniques of cell growth curve… Expand Hainanensine(1) and its analog 6 were obtained through intramolecular regiospecific cycliza-tion. Reduction of 6 under different… Expand A synthetic analogue of hainanensine 2a was further modified in order to improve its antitumor activity. Six compounds 3-8, were… Expand