hainanensine

Known as: 1H-Cyclopenta(jk)(1,3)dioxolo(4,5-h)pyrrolo(2,1-b)(3)benzazepin-1-one, 2,7,8,10,11,12-hexahydro-2-hydroxy-2-methyl-

National Institutes of Health

Papers overview

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2010

A facile total synthesis of hainanensine (1), a structurally unique Cephalotaxus alkaloid, via an effective acid-mediated…

1998

The metabolism of HH07A in the rat has been investigated by GC-MS. After oral administration of HH07A, the rat urine was passed…

1997

The metabolism of hainanensine derivative HH07A has been studied in vitro with rat microsomes. A method of HPLC-DAD was developed…

1997

The effect of HH07A on DNA polymerase I in a cell free system was studied. The results showed that HH07A strongly inhibited the…

1995

The effect of HH07A on the growth of tumor cells in vitro was jnvestigated usingthe techniques of cell growth…

1995

The L1210 cells rapidly ceased to proliferate and its mitotic index decreased markedly after being exposed to HH07A 2 micrograms…

1995

The effect of HH07A on the growth of tumor cells in vitro was investigated using the techniques of cell growth curve…

1993

Hainanensine(1) and its analog 6 were obtained through intramolecular regiospecific cycliza-tion. Reduction of 6 under different…

1992

A synthetic analogue of hainanensine 2a was further modified in order to improve its antitumor activity. Six compounds 3-8, were…

1981