hainanensine

Known as: 1H-Cyclopenta(jk)(1,3)dioxolo(4,5-h)pyrrolo(2,1-b)(3)benzazepin-1-one, 2,7,8,10,11,12-hexahydro-2-hydroxy-2-methyl- 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1981-2010
012319812010

Papers overview

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2010
2010
A facile total synthesis of hainanensine (1), a structurally unique Cephalotaxus alkaloid, via an effective acid-mediated… (More)
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1998
1998
The metabolism of HH07A in the rat has been investigated by GC-MS. After oral administration of HH07A, the rat urine was passed… (More)
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1997
1997
The metabolism of hainanensine derivative HH07A has been studied in vitro with rat microsomes. A method of HPLC-DAD was developed… (More)
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1997
1997
The effect of HH07A on DNA polymerase I in a cell free system was studied. The results showed that HH07A strongly inhibited the… (More)
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1997
1997
The synthesis of DNA, RNA and protein in L1210 cells was inhibited by HH07A in a dose-dependent and time-dependent way. HH07A… (More)
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1995
1995
The L1210 cells rapidly ceased to proliferate and its mitotic index decreased markedly after being exposed to HH07A 2 micrograms… (More)
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1995
1995
The effect of HH07A on the growth of tumor cells in vitro was investigated using the techniques of cell growth curve… (More)
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1992
1992
A synthetic analogue of hainanensine 2a was further modified in order to improve its antitumor activity. Six compounds 3-8, were… (More)
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1981