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guselkumab

National Institutes of Health

Papers overview

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2020
2020
This open‐label, multicenter, phase I therapeutic protein‐drug interaction study was designed to evaluate the potential effect of… 
2020
2020
Abstract Background The fully human monoclonal antibody guselkumab is an effective treatment option for patients with moderate to… 
Review
2020
Review
2020
Background To investigate the efficacy and safety of guselkumab in the treatment of moderate-to-severe plaque psoriasis. Methods… 
Review
2019
Review
2019
ABSTRACT Introduction: Guselkumab is a subcutaneously administered monoclonal antibody that targets the IL-23p19 cytokine subunit… 
2019
2019
Background: Ustekinumab (UST) is a monoclonal antibody (mAb) that binds the p40 epitope which is shared by IL12 and IL23, whereas… 
2019
2019
Background Guselkumab (GUS, an antibody against IL-23) and secukinumab (SEC, an antibody against IL-17A) are both approved for… 
2018
2018
The interleukin (IL)‐23/IL‐17 pathway is central in the pathogenesis of psoriasis. The favourable efficacy and safety of… 
Review
2018
Review
2018
Further understanding of psoriasis pathogenesis has led to the development of effective biologic medications. Guselkumab (GUS) is… 
Review
2018
Review
2018
Objective: Guselkumab, an anti-interleukin-23 monoclonal antibody was recently approved for the treatment of patients with…