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guselkumab
National Institutes of Health
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Broader (1)
Monoclonal Antibodies
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Evaluating Potential Disease‐Mediated Protein‐Drug Interactions in Patients With Moderate‐to‐Severe Plaque Psoriasis Receiving Subcutaneous Guselkumab
Yaowei Zhu
,
Yan Xu
,
+6 authors
Amarnath Sharma
Clinical and Translational Science
2020
Corpus ID: 218649317
This open‐label, multicenter, phase I therapeutic protein‐drug interaction study was designed to evaluate the potential effect of…
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2020
2020
Cost per responder analysis of guselkumab versus targeted therapies in the treatment of moderate to severe plaque psoriasis in Germany
M. Augustin
,
D. Wirth
,
J. Mahlich
,
A. N. Pepper
,
C. Druchok
Journal of dermatological treatment (Print)
2020
Corpus ID: 220529033
Abstract Background The fully human monoclonal antibody guselkumab is an effective treatment option for patients with moderate to…
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Review
2020
Review
2020
Assessing the Short-Term Efficacy and Safety of Guselkumab for Moderate-to-Severe Plaque Psoriasis: Meta-Analysis of Randomized Controlled Trials
Jing Yang
,
Zongming Wang
,
Xilin Zhang
Journal of Immunological Research
2020
Corpus ID: 220833146
Background To investigate the efficacy and safety of guselkumab in the treatment of moderate-to-severe plaque psoriasis. Methods…
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Review
2019
Review
2019
Guselkumab for the treatment of adults with moderate to severe plaque psoriasis
L. Puig
Expert Review of Clinical Immunology
2019
Corpus ID: 85563669
ABSTRACT Introduction: Guselkumab is a subcutaneously administered monoclonal antibody that targets the IL-23p19 cytokine subunit…
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2019
2019
THU0052 USTEKINUMAB AND GUSELKUMAB TREATMENT RESULTS IN DIFFERENCES IN SERUM IL17A, IL17F AND CRP LEVELS IN PSORIATIC ARTHRITIS PATIENTS: A COMPARISON FROM USTEKINUMAB PH3 AND GUSELKUMAB PH2 PROGRAMS
S. Siebert
,
M. Loza
,
Q. Song
,
I. McInnes
,
K. Sweet
Poster Presentations
2019
Corpus ID: 196515256
Background: Ustekinumab (UST) is a monoclonal antibody (mAb) that binds the p40 epitope which is shared by IL12 and IL23, whereas…
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2019
2019
Maintenance of Response With up to 4 Years of Continuous Guselkumab Treatment: Results From the VOYAGE 1 Phase 3 Trial
C. Griffiths
,
K. Papp
,
+5 authors
A. Blauvelt
SKIN The Journal of Cutaneous Medicine
2019
Corpus ID: 209239101
Abstract not available.
2019
2019
SAT0390 GUSELKUMAB WAS MORE EFFECTIVE THAN SECUKINUMAB IN PATIENTS WITH PLAQUE PSORIASIS AND THE SUBSET OF PATIENTS WITH SELF-REPORTED PSORIATIC ARTHRITIS IN THE RANDOMIZED, DOUBLE-BLIND, HEAD-TO…
J. Merola
,
L. Shu
,
+4 authors
L. Coates
Saturday, 15 June
2019
Corpus ID: 190900430
Background Guselkumab (GUS, an antibody against IL-23) and secukinumab (SEC, an antibody against IL-17A) are both approved for…
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2018
2018
Safety and efficacy of guselkumab in Japanese patients with moderate‐to‐severe plaque psoriasis: a randomized, placebo‐controlled, ascending‐dose study
O. Nemoto
,
K. Hirose
,
S. Shibata
,
Kathy Li
,
Hiroshi Kubo
British Journal of Dermatology
2018
Corpus ID: 4437927
The interleukin (IL)‐23/IL‐17 pathway is central in the pathogenesis of psoriasis. The favourable efficacy and safety of…
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Review
2018
Review
2018
Targeting p19 as a treatment option for psoriasis: an evidence-based review of guselkumab
Todd Wechter
,
A. Cline
,
S. Feldman
Therapeutics and Clinical Risk Management
2018
Corpus ID: 52141992
Further understanding of psoriasis pathogenesis has led to the development of effective biologic medications. Guselkumab (GUS) is…
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Review
2018
Review
2018
Treating Moderate-to-Severe Plaque Psoriasis With Guselkumab: A Review of Phase II and Phase III Trials
Seth Howell
,
L. Cardwell
,
S. Feldman
The Annals of Pharmacotherapy
2018
Corpus ID: 206644141
Objective: Guselkumab, an anti-interleukin-23 monoclonal antibody was recently approved for the treatment of patients with…
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