growth differentiation factor 5

Tendon tissue engineering with a biomaterial scaffold that mimics the tendon extracellular matrix (ECM) and is biomechanically… Expand

OBJECTIVES Adipose-derived mesenchymal stem cells (ADMSCs) are a unique population of stem cells with therapeutic potential in… Expand

OBJECTIVES Growth/differentiation factor-5 (GDF-5), a member of the transforming growth factor-beta superfamily, shows a close… Expand

The aim of this study was to examine the role of one of the growth/differentiation factors, GDF-5, in the process of tendon… Expand

BACKGROUND Growth/differentiation factor-5 (GDF-5) has been shown to be essential for normal appendicular skeletal and joint… Expand

Recent studies of intracellular signal transduction mechanisms for the transforming growth factor-beta (TGF-beta) superfamily… Expand

Mutations in GDF-5, a member of the TGF-beta superfamily, result in the autosomal recessive syndromes brachypod (bp) in mice and… Expand

Bone morphogenetic proteins (BMPs) constitute a large family of secreted signals involved in the formation of the skeleton but… Expand

Little is known about the regulatory signals involved in tendon and ligament formation, and this lack of understanding has… Expand

Bone morphogenetic proteins (BMPs) are multifunctional cytokines, which induce bone and cartilage formation and exert various… Expand