FAQ

growth differentiation factor 5

Known as: Cartilage-Derived Morphogenetic Protein-1, CDMP-1, Growth Differentiation Factor 5 [Chemical/Ingredient] 
A growth differentiation factor that plays a role in early CHONDROGENESIS and joint formation.
National Institutes of Health

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1994-2017
012319942017

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GDF5 geneIn BloodProcess of secretionadministration & dosage
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GDF5 protein, human

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1936-2018
19401960198020002020
growth differentiation factor 5
physiological aspects
agonists
chemical synthesis
standards characteristics
Process of secretion

Papers overview

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2015
2015
Supplementation of growth differentiation factor-5 increases proliferation and size of chondrogenic pellets of human umbilical cord-derived perivascular stem cells
In recent years, perivascular stem cells (PVCs) have gained increasing attention as a promising source for regenerative medicine… (More)
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2012
2012
Effect of growth differentiation factor 5 on the proliferation and tenogenic differentiation potential of human mesenchymal stem cells in vitro.
The use of growth differentiation factor 5 (GDF-5) in damaged tendons has been shown to improve tendon repair. It has been… (More)
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2011
2011
Human mesenchymal stem cells induced by growth differentiation factor 5: an improved self-assembly tissue engineering method for cartilage repair.
Previous studies have shown that novel scaffold-free self-assembled constructs can be an ideal alternative for cartilage tissue… (More)
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2010
2010
Augmentation of zone II flexor tendon repair using growth differentiation factor 5 in a rabbit model.
PURPOSE Modulation of zone II flexor tendon repair healing using growth factors may reduce the incidence of complications, such… (More)
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2007
2007
Analysis of osteochondro-induction using growth and differentiation factor-5 in rat muscle.
Growth and differentiation factor-5 (GDF-5) belongs to the TGF-beta super family, and reportedly plays an important role in… (More)
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2006
2006
The effect of intracavernosal growth differentiation factor-5 therapy in a rat model of cavernosal nerve injury.
OBJECTIVE To determine whether the intracavernosal application of growth differentiation factor-5 (GDF-5) influences nerve… (More)
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2004
2004
Neuroprotective effects of delayed administration of growth/differentiation factor-5 in the partial lesion model of Parkinson's disease.
Neurotrophic factors have the potential for therapeutic use in Parkinson's disease (PD) to support the remaining dopaminergic… (More)
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2001
2001
A growth and differentiation factor-5 (GDF-5)-coated suture stimulates tendon healing in an Achilles tendon model in rats.
Growth and differentiation factor-5 (GDF-5) is essential for normal skeletal development and induces tendon-and ligament-like… (More)
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1999
1999
Expression and function of Gdf-5 during digit skeletogenesis in the embryonic chick leg bud.
Bone morphogenetic proteins (BMPs) constitute a large family of secreted signals involved in the formation of the skeleton but… (More)
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1997
1997
Characterization of growth/differentiation factor 5 (GDF-5) as a neurotrophic factor for cultured neurons from chicken dorsal root ganglia.
Growth/differentiation factor-5 (GDF-5), a morphogenetic protein, has previously been shown to act as a neurotrophic factor for… (More)
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