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growth differentiation factor 5

Known as: Cartilage-Derived Morphogenetic Protein-1, CDMP-1, Growth Differentiation Factor 5 [Chemical/Ingredient] 
A growth differentiation factor that plays a role in early CHONDROGENESIS and joint formation.
National Institutes of Health

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GDF5 geneIn BloodProcess of secretionagonists

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GDF5 protein, human

Papers overview

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Highly Cited
2011
Highly Cited
2011
Tendon tissue engineering: adipose-derived stem cell and GDF-5 mediated regeneration using electrospun matrix systems.
Tendon tissue engineering with a biomaterial scaffold that mimics the tendon extracellular matrix (ECM) and is biomechanically… 
Highly Cited
2010
Highly Cited
2010
Adipose-derived mesenchymal stem cells treated with growth differentiation factor-5 express tendon-specific markers.
OBJECTIVES Adipose-derived mesenchymal stem cells (ADMSCs) are a unique population of stem cells with therapeutic potential in… 
Highly Cited
2003
Highly Cited
2003
Effects of growth/differentiation factor-5 on human periodontal ligament cells.
OBJECTIVES Growth/differentiation factor-5 (GDF-5), a member of the transforming growth factor-beta superfamily, shows a close… 
Review
2001
Review
2001
Growth/Differentiation Factor-5 (GDF-5) and Skeletal Development
Background: Growth/differentiation factor-5 (GDF-5) has been shown to be essential for normal appendicular skeletal and joint… 
Highly Cited
1999
Highly Cited
1999
Mechanisms of GDF-5 action during skeletal development.
Mutations in GDF-5, a member of the TGF-beta superfamily, result in the autosomal recessive syndromes brachypod (bp) in mice and… 
Highly Cited
1999
Highly Cited
1999
p38 mitogen-activated protein kinase functionally contributes to chondrogenesis induced by growth/differentiation factor-5 in ATDC5 cells.
Recent studies of intracellular signal transduction mechanisms for the transforming growth factor-beta (TGF-beta) superfamily… 
Highly Cited
1998
Highly Cited
1998
Cartilage‐Derived Morphogenetic Proteins and Osteogenic Protein‐1 Differentially Regulate Osteogenesis
Cartilage‐derived morphogenetic proteins‐1 and ‐2 (CDMP‐1 and CDMP‐2) are members of the bone morphogenetic protein (BMP) family… 
Highly Cited
1998
Highly Cited
1998
Presence of cartilage-derived morphogenetic proteins in articular cartilage and enhancement of matrix replacement in vitro.
OBJECTIVE To investigate the effects of the cartilage-derived morphogenetic proteins (CDMPs) in an in vitro cartilage explant… 
Highly Cited
1997
Highly Cited
1997
Ectopic induction of tendon and ligament in rats by growth and differentiation factors 5, 6, and 7, members of the TGF-beta gene family.
Little is known about the regulatory signals involved in tendon and ligament formation, and this lack of understanding has… 
Highly Cited
1997
Highly Cited
1997
Growth/differentiation factor-5 induces angiogenesis in vivo.
Bone morphogenetic proteins (BMPs) are multifunctional cytokines, which induce bone and cartilage formation and exert various… 
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