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growth differentiation factor 5

Known as: Cartilage-Derived Morphogenetic Protein-1, CDMP-1, Growth Differentiation Factor 5 [Chemical/Ingredient] 
A growth differentiation factor that plays a role in early CHONDROGENESIS and joint formation.
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
OBJECTIVES Adipose-derived mesenchymal stem cells (ADMSCs) are a unique population of stem cells with therapeutic potential in… Expand
Highly Cited
2003
Highly Cited
2003
OBJECTIVES Growth/differentiation factor-5 (GDF-5), a member of the transforming growth factor-beta superfamily, shows a close… Expand
Review
2001
Review
2001
Background: Growth/differentiation factor-5 (GDF-5) has been shown to be essential for normal appendicular skeletal and joint… Expand
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Highly Cited
2001
Highly Cited
2001
Localization studies and genetic evidence have implicated cartilage-derived morphogenetic proteins-1, -2 (CDMP-1 and CDMP-2), and… Expand
Highly Cited
1999
Highly Cited
1999
Mutations in GDF-5, a member of the TGF-beta superfamily, result in the autosomal recessive syndromes brachypod (bp) in mice and… Expand
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Highly Cited
1999
Highly Cited
1999
Recent studies of intracellular signal transduction mechanisms for the transforming growth factor-beta (TGF-beta) superfamily… Expand
Highly Cited
1998
Highly Cited
1998
OBJECTIVE To investigate the effects of the cartilage-derived morphogenetic proteins (CDMPs) in an in vitro cartilage explant… Expand
Highly Cited
1998
Highly Cited
1998
Cartilage‐derived morphogenetic proteins‐1 and ‐2 (CDMP‐1 and CDMP‐2) are members of the bone morphogenetic protein (BMP) family… Expand
Highly Cited
1997
Highly Cited
1997
Little is known about the regulatory signals involved in tendon and ligament formation, and this lack of understanding has… Expand
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Highly Cited
1997
Highly Cited
1997
Bone morphogenetic proteins (BMPs) are multifunctional cytokines, which induce bone and cartilage formation and exert various… Expand