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growth differentiation factor 5
Known as:
Cartilage-Derived Morphogenetic Protein-1
, CDMP-1
, Growth Differentiation Factor 5 [Chemical/Ingredient]
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A growth differentiation factor that plays a role in early CHONDROGENESIS and joint formation.
National Institutes of Health
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Related topics
Related topics
10 relations
GDF5 gene
In Blood
Process of secretion
agonists
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Narrower (1)
GDF5 protein, human
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
Adipose-derived mesenchymal stem cells treated with growth differentiation factor-5 express tendon-specific markers.
Andrew H Park
,
M. Hogan
,
Girish S Kesturu
,
R. James
,
G. Balian
,
A. Chhabra
Tissue engineering. Part A
2010
Corpus ID: 42652028
OBJECTIVES Adipose-derived mesenchymal stem cells (ADMSCs) are a unique population of stem cells with therapeutic potential in…
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Highly Cited
2003
Highly Cited
2003
Effects of growth/differentiation factor-5 on human periodontal ligament cells.
T. Nakamura
,
M. Yamamoto
,
M. Tamura
,
Y. Izumi
Journal of periodontal research
2003
Corpus ID: 29647690
OBJECTIVES Growth/differentiation factor-5 (GDF-5), a member of the transforming growth factor-beta superfamily, shows a close…
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Review
2001
Review
2001
Growth/Differentiation Factor-5 (GDF-5) and Skeletal Development
P. Buxton
,
C. Edwards
,
C. Archer
,
P. Francis-West
The Journal of bone and joint surgery. American…
2001
Corpus ID: 9734565
Background: Growth/differentiation factor-5 (GDF-5) has been shown to be essential for normal appendicular skeletal and joint…
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Highly Cited
2001
Highly Cited
2001
Effects of cartilage-derived morphogenetic proteins and osteogenic protein-1 on osteochondrogenic differentiation of periosteum-derived cells.
R. Gruber
,
C. Mayer
,
+4 authors
L. Erlacher
Endocrinology
2001
Corpus ID: 52849654
Localization studies and genetic evidence have implicated cartilage-derived morphogenetic proteins-1, -2 (CDMP-1 and CDMP-2), and…
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Highly Cited
1999
Highly Cited
1999
Mechanisms of GDF-5 action during skeletal development.
P. Francis-West
,
A. Abdelfattah
,
+7 authors
C. Archer
Development
1999
Corpus ID: 15749860
Mutations in GDF-5, a member of the TGF-beta superfamily, result in the autosomal recessive syndromes brachypod (bp) in mice and…
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Highly Cited
1999
Highly Cited
1999
p38 mitogen-activated protein kinase functionally contributes to chondrogenesis induced by growth/differentiation factor-5 in ATDC5 cells.
K. Nakamura
,
T. Shirai
,
S. Morishita
,
S. Uchida
,
K. Saeki-Miura
,
F. Makishima
Experimental cell research
1999
Corpus ID: 26956784
Recent studies of intracellular signal transduction mechanisms for the transforming growth factor-beta (TGF-beta) superfamily…
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Highly Cited
1998
Highly Cited
1998
Presence of cartilage-derived morphogenetic proteins in articular cartilage and enhancement of matrix replacement in vitro.
L. Erlacher
,
C. K. Ng
,
R. Ullrich
,
S. Krieger
,
F. Luyten
Arthritis and rheumatism
1998
Corpus ID: 35056615
OBJECTIVE To investigate the effects of the cartilage-derived morphogenetic proteins (CDMPs) in an in vitro cartilage explant…
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Highly Cited
1998
Highly Cited
1998
Cartilage‐Derived Morphogenetic Proteins and Osteogenic Protein‐1 Differentially Regulate Osteogenesis
L. Erlacher
,
J. Mccartney
,
+4 authors
F. Luyten
Journal of bone and mineral research : the…
1998
Corpus ID: 25307046
Cartilage‐derived morphogenetic proteins‐1 and ‐2 (CDMP‐1 and CDMP‐2) are members of the bone morphogenetic protein (BMP) family…
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Highly Cited
1997
Highly Cited
1997
Ectopic induction of tendon and ligament in rats by growth and differentiation factors 5, 6, and 7, members of the TGF-beta gene family.
N. M. Wolfman
,
G. Hattersley
,
+9 authors
V. Rosen
The Journal of clinical investigation
1997
Corpus ID: 21105748
Little is known about the regulatory signals involved in tendon and ligament formation, and this lack of understanding has…
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Highly Cited
1997
Highly Cited
1997
Growth/differentiation factor-5 induces angiogenesis in vivo.
H. Yamashita
,
A. Shimizu
,
+7 authors
K. Miyazono
Experimental cell research
1997
Corpus ID: 32176229
Bone morphogenetic proteins (BMPs) are multifunctional cytokines, which induce bone and cartilage formation and exert various…
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