growth differentiation factor 5

OBJECTIVES Adipose-derived mesenchymal stem cells (ADMSCs) are a unique population of stem cells with therapeutic potential in… Expand

OBJECTIVES Growth/differentiation factor-5 (GDF-5), a member of the transforming growth factor-beta superfamily, shows a close… Expand

Background: Growth/differentiation factor-5 (GDF-5) has been shown to be essential for normal appendicular skeletal and joint… Expand

Localization studies and genetic evidence have implicated cartilage-derived morphogenetic proteins-1, -2 (CDMP-1 and CDMP-2), and… Expand

Mutations in GDF-5, a member of the TGF-beta superfamily, result in the autosomal recessive syndromes brachypod (bp) in mice and… Expand

Recent studies of intracellular signal transduction mechanisms for the transforming growth factor-beta (TGF-beta) superfamily… Expand

OBJECTIVE To investigate the effects of the cartilage-derived morphogenetic proteins (CDMPs) in an in vitro cartilage explant… Expand

Cartilage‐derived morphogenetic proteins‐1 and ‐2 (CDMP‐1 and CDMP‐2) are members of the bone morphogenetic protein (BMP) family… Expand

Little is known about the regulatory signals involved in tendon and ligament formation, and this lack of understanding has… Expand

Bone morphogenetic proteins (BMPs) are multifunctional cytokines, which induce bone and cartilage formation and exert various… Expand