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GDF5 protein, human

Known as: growth differentiation factor 5, human, LAP-4, Lipopolysaccharide-Associated Protein 4 
Growth/differentiation factor 5 (501 aa, ~55 kDa) is encoded by the human GDF5 gene. This protein is involved in skeletal development.
National Institutes of Health

Related topics

Related topics

13 relations
Cell Differentiation processCell Proliferation Regulatory ProcessExtracellular SpaceGDF5 gene

Broader (1)

growth differentiation factor 5

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
In Vitro Osteogenic Differentiation Enhanced by Zirconia Coated with Nano-Layered Growth and Differentiation Factor-5.
Zirconia (Zr) is also known as a biocompatible material with favorable mechanical properties as well as low plaque adhesion. In… 
2015
2015
Physical interaction of CCN2 with diverse growth factors involved in chondrocyte differentiation during endochondral ossification
CCN family member 2 (CCN2) has been shown to promote the proliferation and differentiation of chondrocytes, osteoblasts… 
2015
2015
Long-Range Communication Network in the Type 1B Bone Morphogenetic Protein Receptor.
Protein-protein interactions are recognized as a fundamental phenomenon that is intimately associated with biological functions… 
2014
2014
Growth and differentiation factor-5 (GDF-5) in the human intervertebral annulus cells and its modulation by IL-1ß and TNF-α in vitro.
2011
2011
High Efficient Expression of Bioactive Human BMP-14 in E. coli Using SUMO Fusion Partner
Bone morphogenetic proteins (BMPs) are cytokines from the TGF-β superfamily, with important roles during embryonic development… 
2009
2009
Regional and cellular localisation of BMPs and their inhibitors’ expression in human fractures
The objective of this study was to determine whether BMP-2 and -14, noggin, and chordin could be detected in human fractures and… 
2004
2004
Angel shaped phalangeal dysplasia, hip dysplasia, and positional teeth abnormalities are part of the brachydactyly C spectrum associated with CDMP-1 mutations
In 1967, Bachman described a “hereditary peripheral dysostosis” which affected a mother and her two children.1 What was later… 
2001
2001
GDF-5 DEFICIENCY IN MICE RESULTS IN DELAYED ACHILLES TENDON HEALING
INTRODUCTION: The Growth and Differentiation Factors (GDFs) represent a distinct subset of the TGF-β family best known for their… 
1999
1999
Minimal promoter components of the human growth/differentiation factor-5 gene.
Growth/differentiation factor-5 (GDF-5) is a new member of the BMP family supposed to be involved in chondrogenesis. We cloned… 
1998
1998
Effects of growth factors on the proliferation of human keratinocytes and fibroblasts in vitro.
Growth/differentiation factor-5 (GDF-5) is a new member of the transforming growth factor-beta (TGF-beta) superfamily of… 
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