GDF5 protein, human

Known as: growth differentiation factor 5, human, LAP-4, Lipopolysaccharide-Associated Protein 4 
Growth/differentiation factor 5 (501 aa, ~55 kDa) is encoded by the human GDF5 gene. This protein is involved in skeletal development.
National Institutes of Health

Papers overview

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2008
2008
The objective of this study was to determine whether BMP-2 and -14, noggin, and chordin could be detected in human fractures and… (More)
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2008
2008
AbstractGrowth/differentiation factor 5 (GDF5) is a secreted growth factor that plays a key regulatory role in embryonic skeletal… (More)
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2005
2005
OBJECTIVES Bone morphogenetic proteins (BMPs) represent a distinct subset of the transforming growth factor-beta family best… (More)
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2004
2004
Neurotrophic factors have the potential for therapeutic use in Parkinson's disease (PD) to support the remaining dopaminergic… (More)
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2003
2003
Bone- and cartilage-derived morphogenetic proteins (BMPs and CDMPs), which are TGFbeta superfamily members, are growth and… (More)
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2001
2001
Acromesomelic dysplasia of the Hunter-Thompson and Grebe types are rare human disorders based on growth/differentiation factor… (More)
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2000
2000
BACKGROUND Osteogenic protein-1/bone morphogenetic protein-7 (OP-1/BMP-7), a member of the transforming growth factor-beta… (More)
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1999
1999
Recent studies of intracellular signal transduction mechanisms for the transforming growth factor-beta (TGF-beta) superfamily… (More)
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Highly Cited
1999
Highly Cited
1999
Mutations in GDF-5, a member of the TGF-beta superfamily, result in the autosomal recessive syndromes brachypod (bp) in mice and… (More)
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1996
1996
The TGF-beta superfamily comprises a number of functionally diverse growth factors/signalling molecules (1) which elicit their… (More)
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