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GDF5 protein, human

Known as: growth differentiation factor 5, human, LAP-4, Lipopolysaccharide-Associated Protein 4 
Growth/differentiation factor 5 (501 aa, ~55 kDa) is encoded by the human GDF5 gene. This protein is involved in skeletal development.
National Institutes of Health

Papers overview

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Review
2011
Review
2011
Osteoarthritis (OA) is the most common cause of arthritis and represents an enormous healthcare burden in industrialized… Expand
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Highly Cited
2011
Highly Cited
2011
Tendon tissue engineering with a biomaterial scaffold that mimics the tendon extracellular matrix (ECM) and is biomechanically… Expand
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Highly Cited
2003
Highly Cited
2003
Bone‐ and cartilage‐derived morphogenetic proteins (BMPs and CDMPs), which are TGFβ superfamily members, are growth and… Expand
Highly Cited
2003
Highly Cited
2003
The aim of this study was to examine the role of one of the growth/differentiation factors, GDF‐5, in the process of tendon… Expand
Review
2001
Review
2001
Background: Growth/differentiation factor-5 (GDF-5) has been shown to be essential for normal appendicular skeletal and joint… Expand
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Highly Cited
1999
Highly Cited
1999
Mutations in GDF-5, a member of the TGF-beta superfamily, result in the autosomal recessive syndromes brachypod (bp) in mice and… Expand
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Highly Cited
1999
Highly Cited
1999
Recent studies of intracellular signal transduction mechanisms for the transforming growth factor-beta (TGF-beta) superfamily… Expand
Highly Cited
1996
Highly Cited
1996
Growth/differentiation factor-5 (GDF-5) is a member of the bone morphogenetic protein (BMP) family, which plays an important role… Expand
Highly Cited
1996
Highly Cited
1996
The TGF-β superfamily comprises a number of functionally diverse growth factors/signalling molecules1 which elicit their response… Expand
Highly Cited
1996
Highly Cited
1996
The TGF-beta superfamily comprises a number of functionally diverse growth factors/signalling molecules (1) which elicit their… Expand