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glycogen synthase kinase 3 alpha, human

Known as: Glycogen Synthase Kinase-3 Alpha, GSK-3 Alpha, GSK3-alpha 
Glycogen synthase kinase-3 alpha (483 aa, ~51 kDa) is encoded by the human GSK3A gene. This protein plays a role in protein phosphorylation and… Expand
National Institutes of Health

Related topics

Related topics

16 relations
Carbohydrate MetabolismEnzyme GeneGSK3A geneGSK3A wt Allele
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Broader (2)

Protein Kinasesglycogen synthase kinase 3 alpha

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
Gene Networks Driving Bovine Mammary Protein Synthesis During the Lactation Cycle
A crucial role for both insulin and mTOR in the regulation of milk protein synthesis is emerging. Bovine mammary biopsies… Expand
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Highly Cited
2008
Highly Cited
2008
GSK-3beta in mouse fibroblasts controls wound healing and fibrosis through an endothelin-1-dependent mechanism.
Glycogen synthase kinase-3 (GSK-3) is a widely expressed and highly conserved serine/threonine protein kinase encoded by 2 genes… Expand
2007
2007
Role of glycogen synthase kinase-3 alpha in insulin action in cultured human skeletal muscle cells.
An association between glycogen synthase kinase-3 (GSK3) in skeletal muscle and insulin resistance has been demonstrated in type… Expand
Highly Cited
2007
Highly Cited
2007
Not only lithium: regulation of glycogen synthase kinase-3 by antipsychotics and serotonergic drugs.
  • J. Beaulieu
  • The international journal of…
  • 2007
    • Corpus ID: 15797894
Multiple recent lines of evidence have underscored the potential role of glycogen synthase kinase-3 (GSK3) as a common molecular… Expand
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Highly Cited
2005
Highly Cited
2005
Comparative gene expression analysis of blood and brain provides concurrent validation of SELENBP1 up-regulation in schizophrenia
Microarray techniques hold great promise for identifying risk factors for schizophrenia (SZ) but have not yet generated widely… Expand
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Highly Cited
2005
Highly Cited
2005
Switching on a signaling pathway with an organoruthenium complex.
Altering cellular function with small synthetic molecules is a general approach for the design of drugs (medicinal chemistry) and… Expand
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Highly Cited
2004
Highly Cited
2004
Increased MAP kinase activity in Alzheimer's and Down syndrome but not in schizophrenia human brain
Abnormal phosphorylation of tau is a feature of Alzheimer's disease (AD), which develops prematurely in Down syndrome (DS… Expand
Highly Cited
2004
Highly Cited
2004
Changes in sperm glycogen synthase kinase-3 serine phosphorylation and activity accompany motility initiation and stimulation.
Sperm motility is regulated by protein phosphorylation. We have shown that the signaling kinase, glycogen synthase kinase-3 alpha… Expand
Highly Cited
1998
Highly Cited
1998
Isolation and chromosomal mapping of human glycogen synthase kinase-3 alpha and -3 beta encoding genes.
Glycogen synthase kinase-3 (GSK-3) is a serine-threonine kinase that exists as two isoforms, alpha and beta, encoded by separate… Expand
Highly Cited
1996
Highly Cited
1996
Phosphorylation of tau by glycogen synthase kinase-3β in intact mammalian cells: The effects on the organization and stability of microtubules
The phosphorylation state of tau changes during neurodevelopment and highly phosphorylated tau accumulates in the paired helical… Expand
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