FAQ

glycogen synthase kinase 3 alpha, human

Known as: Glycogen Synthase Kinase-3 Alpha, GSK-3 Alpha, GSK3-alpha 
Glycogen synthase kinase-3 alpha (483 aa, ~51 kDa) is encoded by the human GSK3A gene. This protein plays a role in protein phosphorylation and… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1993-2016
02419932016

Related topics

Related topics

15 relations
Carbohydrate MetabolismEnzyme GeneGSK3A geneGlycogen Synthase Kinase 3
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Broader (2)

Protein Kinasesglycogen synthase kinase 3 alpha

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
glycogen synthase kinase 3 alpha, human
Signal Transduction
Protein Kinases
Homo sapiens
Phosphotransferases
Carbohydrate Metabolism

Papers overview

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2015
2015
Targeted disruption of glycogen synthase kinase 3A (GSK3A) in mice affects sperm motility resulting in male infertility.
The signaling enzyme glycogen synthase kinase 3 (GSK3) exists as two isoforms-GSK3A and GSK3B. Protein phosphorylation by GSK3… (More)
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2012
2012
Distinct expression and activity of GSK-3α and GSK-3β in prostate cancer.
Glycogen synthase kinase (GSK-3) is upregulated in many types of tumor, including prostate cancer. GSK-3 inhibitors reduce… (More)
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2010
2010
Identification and regulation of glycogen synthase kinase-3 during bovine embryo development.
The aim of this study was to examine the presence and regulation of glycogen synthase kinase-3alpha (GSK3A) and GSK-3beta (GSK3B… (More)
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2010
2010
A Pipeline to Determine RT-QPCR Control Genes for Evolutionary Studies: Application to Primate Gene Expression across Multiple Tissues
Because many species-specific phenotypic differences are assumed to be caused by differential regulation of gene expression, many… (More)
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2010
2010
Interactome mapping of the phosphatidylinositol 3-kinase-mammalian target of rapamycin pathway identifies deformed epidermal autoregulatory factor-1 as a new glycogen synthase kinase-3 interactor.
The phosphatidylinositol 3-kinase-mammalian target of rapamycin (PI3K-mTOR) pathway plays pivotal roles in cell survival, growth… (More)
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2008
2008
GSK-3beta in mouse fibroblast controls wound healing and fibrosis through an endothelin-1-dependent mechanism.
Glycogen synthase kinase-3 (GSK-3) is a widely expressed and highly conserved serine/threonine protein kinase encoded by 2 genes… (More)
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2007
2007
Insulin signaling in mouse oocytes.
Continuous exposure of follicles/oocytes to elevated levels of insulin compromises embryonic developmental competence, although… (More)
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Highly Cited
2005
Highly Cited
2005
Comparative gene expression analysis of blood and brain provides concurrent validation of SELENBP1 up-regulation in schizophrenia.
Microarray techniques hold great promise for identifying risk factors for schizophrenia (SZ) but have not yet generated widely… (More)
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2001
2001
The phosphatidylinositide 3'-kinase/Akt survival pathway is a target for the anticancer and radiosensitizing agent PKC412, an inhibitor of protein kinase C.
Activation of the phosphatidylinositol 3'-kinase (PI3K)/Akt survival pathway protects against apoptotic stress stimuli. Therefore… (More)
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Highly Cited
1998
Highly Cited
1998
Mutational analysis of the APC/beta-catenin/Tcf pathway in colorectal cancer.
Mutation of the adenomatous polyposis coli (APC) tumor suppressor gene initiates the majority of colorectal (CR) cancers. One… (More)
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