Skip to search formSkip to main contentSkip to account menu

glutaminyl-peptide cyclotransferase activity

Known as: L-glutaminyl-peptide gamma-glutamyltransferase (cyclizing), glutaminyl cyclase activity, glutaminyl-transfer ribonucleate cyclotransferase activity 
Catalysis of the reaction: L-glutaminyl-peptide = 5-oxoprolyl-peptide + NH3. [EC:2.3.2.5]
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Glutaminyl cyclases (QC) catalyze the formation of neurotoxic pGlu‐modified amyloid‐β peptides found in the brains of people with… 
2016
2016
Abstract Secretory peptides and proteins are frequently modified by pyroglutamic acid (pE, pGlu) at their N-terminus. This… 
Highly Cited
2011
Highly Cited
2011
Acute and chronic inflammatory disorders are characterized by detrimental cytokine and chemokine expression. Frequently, the… 
2004
2004
Summary1.Following the recent demonstration of a glutaminyl cyclase activity localized in adrenomedullary chromaffin vesicles, an… 
Highly Cited
2002
Highly Cited
2002
The enzymatic conversion of one chromogenic substrate, l-glutamine-p-nitroanilide, and two fluorogenic substrates, l-glutaminyl-2… 
1998
1998
that achieved by TLC with numerous buffers (1,2,5) or by HV-TLE protocols (2) when multiple samples are analyzed. We have found… 
1989
1989
  • R. Bateman
  • Journal of Neuroscience Methods
  • 1989
  • Corpus ID: 42726863